ID D6ZKC8_MOBCV Unreviewed; 564 AA.
AC D6ZKC8;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN Name=fliD {ECO:0000313|EMBL:ADI67177.1};
GN OrderedLocusNames=HMPREF0573_10858 {ECO:0000313|EMBL:ADI67177.1};
OS Mobiluncus curtisii (strain ATCC 43063 / DSM 2711 / V125) (Falcivibrio
OS vaginalis).
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Mobiluncus.
OX NCBI_TaxID=548479 {ECO:0000313|EMBL:ADI67177.1, ECO:0000313|Proteomes:UP000006742};
RN [1] {ECO:0000313|Proteomes:UP000006742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43063 / DSM 2711 / V125
RC {ECO:0000313|Proteomes:UP000006742};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R., Gibbs R.;
RT "Complete sequence of Mobiluncus curtisii ATCC 43063.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
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DR EMBL; CP001992; ADI67177.1; -; Genomic_DNA.
DR AlphaFoldDB; D6ZKC8; -.
DR STRING; 548479.HMPREF0573_10858; -.
DR KEGG; mcu:HMPREF0573_10858; -.
DR eggNOG; COG1345; Bacteria.
DR HOGENOM; CLU_015182_4_2_11; -.
DR Proteomes; UP000006742; Chromosome.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:ADI67177.1};
KW Cilium {ECO:0000313|EMBL:ADI67177.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:ADI67177.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006742};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 35..139
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 289..549
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 564 AA; 60796 MW; B5CD4863FBF35750 CRC64;
MPVGVLSLGV ISGWDDTLIP WKEHIMGISI PGLGGFNTQG IVKQLMMLEQ VPLRKLESKQ
NEYKSQVQSL QTMNTKFSNI KRAAWDVYGR ASKESVRFDT AEIWEAAKAT SSDPMVGVTT
TPGAQVGSVE FDVLQVAKSK QATLDLDGVK NLYDAAKAKG EPPKISIMIG DKITTISPSS
ATAPAFARAI NAASDSGISA TSVRVGDNPD GTGKYVLQIT GKETGADKGD FKIFAGDITQ
GLGLNAKTSK TDAATNSAHY VYEDAAALAT AVRNTGVQEQ ALNIIHQSSD AKIRLLGQER
TYGSNEIQIM DHVKIDLSNV VQKTNPDGTP LYTDALLKGV KVNATRDFDV AAGKMEKMMG
ALTDALNTLN RGMQSVTKEG IDPTTNKRFT YTAAGPLGNS EGRELKNKIM GLVSSGITVT
DAEGKSQTYS LSTFGVGFSG GVEKGADGQV HGSQVNLKFD AEKFKKAMES NPEKVQQVMV
EFAKKVGDVA SKVSDFTEGS LTRSIESRQK TVSYYRDRIS EYGDRLDRKE AQLYKQYSSL
ETMLARMQQQ QTWLAGQLSQ LGGQ
//
