ID   D6ZVS9_BIFLJ            Unreviewed;      1704 AA.
AC   D6ZVS9;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Putative CoA-substrate-specific enzyme activase {ECO:0000313|EMBL:ADH00985.1};
GN   OrderedLocusNames=BLJ_1542 {ECO:0000313|EMBL:ADH00985.1};
OS   Bifidobacterium longum subsp. longum (strain JDM301).
OC   Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=759350 {ECO:0000313|EMBL:ADH00985.1, ECO:0000313|Proteomes:UP000006740};
RN   [1] {ECO:0000313|EMBL:ADH00985.1, ECO:0000313|Proteomes:UP000006740}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JDM301 {ECO:0000313|EMBL:ADH00985.1,
RC   ECO:0000313|Proteomes:UP000006740};
RX   PubMed=20525832; DOI=10.1128/JB.00538-10;
RA   Wei Y.X., Zhang Z.Y., Liu C., Zhu Y.Z., Zhu Y.Q., Zheng H., Zhao G.P.,
RA   Wang S., Guo X.K.;
RT   "Complete genome sequence of Bifidobacterium longum JDM301.";
RL   J. Bacteriol. 192:4076-4077(2010).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR   EMBL; CP002010; ADH00985.1; -; Genomic_DNA.
DR   RefSeq; WP_013141179.1; NC_014169.1.
DR   KEGG; bll:BLJ_1542; -.
DR   HOGENOM; CLU_002393_1_0_11; -.
DR   Proteomes; UP000006740; Chromosome.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.40; -; 4.
DR   InterPro; IPR002731; ATPase_BadF.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR018709; CoA_activase_DUF2229.
DR   InterPro; IPR008275; CoA_E_activase_dom.
DR   NCBIfam; TIGR00241; CoA_E_activ; 1.
DR   PANTHER; PTHR32329:SF4; ACTIVATOR OF 2-HYDROXYACYL-COA DEHYDRATASE-RELATED; 1.
DR   PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR   Pfam; PF01869; BcrAD_BadFG; 2.
DR   Pfam; PF09989; DUF2229; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Iron {ECO:0000256|ARBA:ARBA00023014};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00023014}.
FT   DOMAIN          21..279
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          351..605
FT                   /note="ATPase BadF/BadG/BcrA/BcrD type"
FT                   /evidence="ECO:0000259|Pfam:PF01869"
FT   DOMAIN          753..971
FT                   /note="DUF2229"
FT                   /evidence="ECO:0000259|Pfam:PF09989"
FT   REGION          623..648
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1166..1197
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1233..1258
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          1109..1161
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1704 AA;  185502 MW;  8AE925DDE7E393AC CRC64;
     MVDIVTDASV KPASHPKPLR VGLDIGSTTV KAVVLDQSDS LKDTLFSDYR RHHANVRATV
     AGLLVDIRKE LVELGRGDEP IRLSITGSGG LALADNLHVP FIQEVIAETE AIDKEYPQAD
     VIIELGGEDA KITYLKPTPE QRMNGSCAGG TGAFIDQMST LLDTDAAGLN EMAKSYENLY
     PIASRCGVFA KTDLQPLIND GAAKPDLAAS IFTAVATQTI AGLAAGRPIH GTVIFLGGPL
     FFMSELRAAF QRALEGKVDE FIVPTDAHLY VAYGSALQAD MDSDDQGHHF EAHTCDEILM
     RLDELKNLPS NTPTMPPLFP TEADREDFNK RHHKEHIHIG TLEGAHGPHF LGIDAGSTTI
     KATLVNDDRE IVWSSYANNE GSPLTAAINI VKKIQSELPE GAWIARSCAT GYGEGLITTG
     LHLDEGVVET MAHYRGAEMV SPGVTAVIDI GGQDMKYLAI TDGVIDSIAV NEACSSGCGS
     FLQTFAMSMG LTIQEFTQKA LASTHPVDLG SRCTVFMNSS VKQAQKEGAS IEDIAAGLCY
     SVVRNALYKV IKLRDSGELG DTVVVQGGTF LNDAVLRAFE LLTERQVTRP NIAGLMGAFG
     AALTARMHYQ DEADHLDVVV KADGSEEQSE AEPAPKSEPK AAAFKKTEPA KPEAHVVVVD
     GVTHTASSIL TGEALDNMSM TAERDVCKLC QNHCKLTITT FSDGSRFVTG NRCERGGDAK
     KKRSDRPNLY DYKYKRCFAY RRLTDKKATR GEIGIPRALN MYENYPFWFT LLTTLGFKVM
     ISGRSSHELF ETGIESIASE NICYPAKLVH GHIKWLINKG IKTIFYPCVS YEENLVPNTD
     NHYNCPVVAN YPLVVGANVP ELREDGVRYM HPYFNLANHE LMVDRIVEEF AWANVTREEA
     ETAVKAAYAE DKVFKHDVQQ EGLTALAYMK EHNCRGIVLA GRPYHIDPEI NHGIPETICS
     LGMVVLSEDS ICELHPGEKL NLTEFLSEGE ADPRSKNAAR FRHVGDRTVT KMPLRVTNQW
     AYHSRLYAAA HFVASYPGLE LVQLNSFGCG LDAITTDQVA EILADKADVY TLLKIDEVSN
     LGAAKIRLRS LKAAVEEREA NKAREAAAAK AMEDQQAAAE RAAEEAKVKA ESDLEAAKAA
     LAEAQAAVEA AQKKVDAEAQ AVHDAAKASQ ASTAKAVQGP KPTGFRKTGP TAPTPGRQIL
     LDSTMAANPK LTKAMREASK RAAERDLQAA VANKNGTSDG TTGVTNAKNA KKSGHNNATM
     SRYAHREKFV KDMKKNYTIV GPQMSPIHMS LVEAVIRSGG YKFDILKHAS RGDVETGLKY
     VNNDACYPAI MVVGQLIDAI LEGKYDPDHV ALAITQTGGM CRATNYFGLI RKALVDAGYP
     QIPVIAISTQ GLEDNPGFKA TLPLLHRAIK ALILGDLLMK CLYRVRPYEV EKGSANKLYE
     LWDTIVRETI EHHGYSKTAA KTPSIKKGYL PYNVLAKEIV KSFDNLPLRD IPRKVRVGVV
     GEILVKYQPD ANNHVVDVIE SQDCEAVVPG IMEFMTTRPY ITDWNEKNLG MGGNKTLYAL
     MRKGLDLYNA PIKAALVTSR GKFKQDEPMP ELVKKAAEVT SIGVQAGEGW LLTAEILELI
     EQGCPNVICA QPFACLPNHV TGRGMFGKIR RLHPEANIVS IDYDPGASEA NQLNRIKLMI
     AAAKKAHNAK FAEAGEPQGF TSAD
//