ID D7BV19_STRBB Unreviewed; 681 AA.
AC D7BV19;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Short chain dehydrogenase {ECO:0000313|EMBL:ADI05398.1};
GN OrderedLocusNames=SBI_02277 {ECO:0000313|EMBL:ADI05398.1};
OS Streptomyces bingchenggensis (strain BCW-1).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI05398.1, ECO:0000313|Proteomes:UP000000377};
RN [1] {ECO:0000313|EMBL:ADI05398.1, ECO:0000313|Proteomes:UP000000377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCW-1 {ECO:0000313|EMBL:ADI05398.1,
RC ECO:0000313|Proteomes:UP000000377};
RX PubMed=20581206; DOI=10.1128/JB.00596-10;
RA Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA Xiang W.S.;
RT "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT bingchenggensis.";
RL J. Bacteriol. 192:4526-4527(2010).
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484}.
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DR EMBL; CP002047; ADI05398.1; -; Genomic_DNA.
DR RefSeq; WP_014174877.1; NC_016582.1.
DR AlphaFoldDB; D7BV19; -.
DR STRING; 749414.SBI_02277; -.
DR KEGG; sbh:SBI_02277; -.
DR PATRIC; fig|749414.3.peg.2353; -.
DR eggNOG; COG1028; Bacteria.
DR eggNOG; COG3347; Bacteria.
DR HOGENOM; CLU_024866_0_0_11; -.
DR Proteomes; UP000000377; Chromosome.
DR CDD; cd08943; R1PA_ADH_SDR_c; 1.
DR Gene3D; 3.40.225.10; Class II aldolase/adducin N-terminal domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001303; Aldolase_II/adducin_N.
DR InterPro; IPR036409; Aldolase_II/adducin_N_sf.
DR InterPro; IPR013454; Bifunc_RhaD/ADH.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR NCBIfam; TIGR02632; RhaD_aldol-ADH; 1.
DR PANTHER; PTHR43669; 5-KETO-D-GLUCONATE 5-REDUCTASE; 1.
DR PANTHER; PTHR43669:SF8; SHORT-CHAIN TYPE DEHYDROGENASE_REDUCTASE-RELATED; 1.
DR Pfam; PF00106; adh_short; 1.
DR Pfam; PF00596; Aldolase_II; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SMART; SM01007; Aldolase_II; 1.
DR SUPFAM; SSF53639; AraD/HMP-PK domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000377}.
FT DOMAIN 11..213
FT /note="Class II aldolase/adducin N-terminal"
FT /evidence="ECO:0000259|SMART:SM01007"
FT REGION 15..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 681 AA; 72333 MW; DAA172F8AA657B63 CRC64;
MTAEPHPEAA TLLERSHRLG ADPRNTNYAG GNTSAKGTAT DPVTGQDVDL MWVKGSGGDL
GTLTEAGLAA LRLDRLRALT EVYPGVERED EMVAAFDFCL HGKGGAAPSI DTAMHGLVNA
AHVDHLHPDS GIALACAADG EALTKECFGN QVVWVPWRRP GFQLGLDIAA IKKANPEAIG
CILGGHGITA WGDTSDECEA NSLRIIRTAE QFLVERGKSD PFGPVVPGYE PLPEAERRAR
AAALAPVLRG LASTDRPQVG HYNDSDPVLD FVSRAEHPRL AALGTSCPDH FLRTKVRPLV
LDLPPTTPLD EAIARLKELH TAYRTDYQAY YERHATPDSP AMRGADPAVV LIPGVGMFSY
GKDKQTARVA GEFYVNAINV MRGAEAVSTY SPIEESEKFR IEYWALEEAK LQRMPKPKPL
ATRIALVTGA GSGIGKAIAN RLVAEGACVV VADINADNAA TVAAELGGPD KAVPVTVDIT
SEEQIKTAFD QAVLAFGGVD LLVNNAGISI SKPLLETTAK DWDLQHDIMA RGSFLSSREA
ARVMIDQNMG GDIIYIASKN SIFAGPNNIA YSATKADQAH QVRLLAAELG AHGIRVNGVN
PDGVVQGSGI FAGGWGAQRA ATYGIPEEEL GKFYAQRTLL KREVLPEHVA NAVFALTGGD
LTHTTGLHVP VDAGVAAAFL R
//
