ID D7C241_STRBB Unreviewed; 220 AA.
AC D7C241;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Transcriptional regulator, TetR family protein {ECO:0000313|EMBL:ADI12242.1};
GN OrderedLocusNames=SBI_09124 {ECO:0000313|EMBL:ADI12242.1};
OS Streptomyces bingchenggensis (strain BCW-1).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI12242.1, ECO:0000313|Proteomes:UP000000377};
RN [1] {ECO:0000313|EMBL:ADI12242.1, ECO:0000313|Proteomes:UP000000377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCW-1 {ECO:0000313|EMBL:ADI12242.1,
RC ECO:0000313|Proteomes:UP000000377};
RX PubMed=20581206; DOI=10.1128/JB.00596-10;
RA Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA Xiang W.S.;
RT "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT bingchenggensis.";
RL J. Bacteriol. 192:4526-4527(2010).
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DR EMBL; CP002047; ADI12242.1; -; Genomic_DNA.
DR RefSeq; WP_014181689.1; NC_016582.1.
DR AlphaFoldDB; D7C241; -.
DR STRING; 749414.SBI_09124; -.
DR KEGG; sbh:SBI_09124; -.
DR PATRIC; fig|749414.3.peg.9399; -.
DR eggNOG; COG1309; Bacteria.
DR HOGENOM; CLU_069543_5_1_11; -.
DR Proteomes; UP000000377; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR004111; Repressor_TetR_C.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF151; HTH-TYPE TRANSCRIPTIONAL REPRESSOR RV1353C; 1.
DR Pfam; PF02909; TetR_C_1; 1.
DR Pfam; PF00440; TetR_N; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000000377};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 18..78
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 41..60
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 220 AA; 24565 MW; 68ED0A8E6B68CB61 CRC64;
MAQQADGTAR RGRGRPPRLS RDQIVRAAAE LAAREPGVVL TIKRVAEAVD SAPMALYRYF
PDRDDLLQAV ADRIIADAEH TEPPGDTWQD QLRAWMHTSR ERLRPYRQLL SYMAATEQPA
WVPALVTLTR VLRPLRLGED ELALAVTLVC STVIGHAVYE THRRPAEQKM AGLREALALR
PQEEQEAVAP LLPRLPDAQR RLYDVVVDRT IAAVEALATG
//
