ID D7E898_METEZ Unreviewed; 325 AA.
AC D7E898;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Biotin/acetyl-CoA-carboxylase ligase {ECO:0000313|EMBL:ADI73440.1};
DE EC=6.3.4.15 {ECO:0000313|EMBL:ADI73440.1};
GN OrderedLocusNames=Metev_0528 {ECO:0000313|EMBL:ADI73440.1};
OS Methanohalobium evestigatum (strain ATCC BAA-1072 / DSM 3721 / NBRC 107634
OS / OCM 161 / Z-7303).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanohalobium.
OX NCBI_TaxID=644295 {ECO:0000313|EMBL:ADI73440.1, ECO:0000313|Proteomes:UP000000391};
RN [1] {ECO:0000313|EMBL:ADI73440.1, ECO:0000313|Proteomes:UP000000391}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1072 / DSM 3721 / NBRC 107634 / OCM 161 / Z-7303
RC {ECO:0000313|Proteomes:UP000000391};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Saunders E., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Anderson I.,
RA Woyke T.;
RT "Complete sequence chromosome of Methanohalobium evestigatum Z-7303.";
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002069; ADI73440.1; -; Genomic_DNA.
DR RefSeq; WP_013194008.1; NC_014253.1.
DR AlphaFoldDB; D7E898; -.
DR STRING; 644295.Metev_0528; -.
DR GeneID; 9346149; -.
DR KEGG; mev:Metev_0528; -.
DR HOGENOM; CLU_051096_0_0_2; -.
DR OrthoDB; 46252at2157; -.
DR Proteomes; UP000000391; Chromosome.
DR GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16442; BPL; 1.
DR Gene3D; 2.30.30.100; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_00978; Bifunct_BirA; 1.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR030855; Bifunct_BirA.
DR InterPro; IPR004408; Biotin_CoA_COase_ligase.
DR InterPro; IPR003142; BPL_C.
DR InterPro; IPR004143; BPL_LPL_catalytic.
DR InterPro; IPR013196; HTH_11.
DR InterPro; IPR008988; Transcriptional_repressor_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00121; birA_ligase; 1.
DR PANTHER; PTHR12835; BIOTIN PROTEIN LIGASE; 1.
DR PANTHER; PTHR12835:SF5; BIOTIN--PROTEIN LIGASE; 1.
DR Pfam; PF02237; BPL_C; 1.
DR Pfam; PF03099; BPL_LplA_LipB; 1.
DR Pfam; PF08279; HTH_11; 1.
DR SUPFAM; SSF50037; C-terminal domain of transcriptional repressors; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51733; BPL_LPL_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ADI73440.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000391}.
FT DOMAIN 70..258
FT /note="BPL/LPL catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51733"
SQ SEQUENCE 325 AA; 36057 MW; F176AE858485D96F CRC64;
MSDRKEDILN ILKNSDQKPV SGEELGEQLG ISRTMVWKYI KSLKDDGYNI TSSTKTGYIL
NSSPDMLYSE EILSGLKTSI IGNKIYHFDE LESTNEEAKR LAPDEDEGTV IISETQKSGR
GRMGRDWTSP RGGIYMSVIL KPTIPASHAY HLTLVAGIAV ANAIRNLGIN ACIKWPNDIL
INNRKVCGIL TEINAEIEKI DYIVLGMGIN ANVDTGMFSS ELKEGSTSLK SELGKPVERV
SFVQNLLYEF EQEYIKFKSK PFNDIVDEWI SLSDTIGKEV SIMTPSKMVE GKAIGVTKNG
ALIVKKDDGE KEEIIAGRCI YTRTS
//
