ID D7EAD2_METEZ Unreviewed; 386 AA.
AC D7EAD2;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Peptidase M24 {ECO:0000313|EMBL:ADI74931.1};
GN OrderedLocusNames=Metev_2104 {ECO:0000313|EMBL:ADI74931.1};
OS Methanohalobium evestigatum (strain ATCC BAA-1072 / DSM 3721 / NBRC 107634
OS / OCM 161 / Z-7303).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanohalobium.
OX NCBI_TaxID=644295 {ECO:0000313|EMBL:ADI74931.1, ECO:0000313|Proteomes:UP000000391};
RN [1] {ECO:0000313|EMBL:ADI74931.1, ECO:0000313|Proteomes:UP000000391}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1072 / DSM 3721 / NBRC 107634 / OCM 161 / Z-7303
RC {ECO:0000313|Proteomes:UP000000391};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Saunders E., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Anderson I.,
RA Woyke T.;
RT "Complete sequence chromosome of Methanohalobium evestigatum Z-7303.";
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|RuleBase:RU000590}.
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DR EMBL; CP002069; ADI74931.1; -; Genomic_DNA.
DR AlphaFoldDB; D7EAD2; -.
DR STRING; 644295.Metev_2104; -.
DR KEGG; mev:Metev_2104; -.
DR HOGENOM; CLU_017266_4_3_2; -.
DR OrthoDB; 1346at2157; -.
DR Proteomes; UP000000391; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR001131; Peptidase_M24B_aminopep-P_CS.
DR PANTHER; PTHR46112; AMINOPEPTIDASE; 1.
DR PANTHER; PTHR46112:SF2; XAA-PRO AMINOPEPTIDASE P-RELATED; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
DR PROSITE; PS00491; PROLINE_PEPTIDASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000590};
KW Reference proteome {ECO:0000313|Proteomes:UP000000391}.
FT DOMAIN 5..139
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 150..371
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
SQ SEQUENCE 386 AA; 43396 MW; B31EDD1880DB1428 CRC64;
MDISNTLSKK GLDAYMMIGE PHNADMYYTT GFFASDKFTY LQKNSGDEIL LVSEMERERA
ENESRITNIR TTQDYDYRSK IKSRSDPSIA FSDTLGELLG KEGIRKIGVP HNFPFFIAQT
LKEQGFWFMP IKSPFKDMRT KKSESEITNI ETVQNACEEA MDTAVNLISN SSESDGVLYN
EGVELTSEYV RNAIEHRLLD FGCEAETTIV ACGKQSSTPH WMGEGTLKVN EPIIIDIFPR
SKTNRYFSDM SRTVVKGTPS RQLKDMYDAV IEAQNKALEL VKPGVLCNEI HNAVCDVFEE
KGYDTVRNNP KLKSGFLHST GHGVGLEVHE LPSLGDNENQ LESGNVITVE PGLYYPDIGG
VRIEDIVVVT EKGCRNLTEF EKKFVV
//
