ID D7G6X2_ECTSI Unreviewed; 738 AA.
AC D7G6X2;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Methyltransferase {ECO:0000313|EMBL:CBJ25665.1};
GN ORFNames=Esi_0008_0070 {ECO:0000313|EMBL:CBJ25665.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBJ25665.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBJ25665.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
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DR EMBL; FN649035; CBJ25665.1; -; Genomic_DNA.
DR AlphaFoldDB; D7G6X2; -.
DR STRING; 2880.D7G6X2; -.
DR EnsemblProtists; CBJ25665; CBJ25665; Esi_0008_0070.
DR eggNOG; KOG4626; Eukaryota.
DR InParanoid; D7G6X2; -.
DR OrthoDB; 91541at2759; -.
DR Proteomes; UP000002630; Chromosome LG02.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR013216; Methyltransf_11.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44523; TETRATRICOPEPTIDE REPEAT PROTEIN 13; 1.
DR PANTHER; PTHR44523:SF1; TETRATRICOPEPTIDE REPEAT PROTEIN 13; 1.
DR Pfam; PF08241; Methyltransf_11; 1.
DR Pfam; PF13414; TPR_11; 1.
DR Pfam; PF07719; TPR_2; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 3.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:CBJ25665.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Signal {ECO:0000256|SAM:SignalP};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transferase {ECO:0000313|EMBL:CBJ25665.1}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..738
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003096215"
FT REPEAT 292..325
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 326..359
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 435..468
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 562..655
FT /note="Methyltransferase type 11"
FT /evidence="ECO:0000259|Pfam:PF08241"
FT REGION 34..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 658..689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 738 AA; 80169 MW; 9D0196CACEC908B3 CRC64;
MRCCSLAGVD VALLLLAGAA RSGEAFLFSG LRVPSTPRRQ HDPSPSSNTQ QQHAASGGRL
LPTTSRPPST ASTLRATPAD DATGQQILEY PGMTDDQEGG APEGRQEGAA QPPPIPKDTT
RRAVALDGTA LAFRPPTTQD FHKLGMGDWV AQKGLAVALV ALGATEQAAG EPVIGAPLAG
AVVEAMGGGS SVATQVCLLR HRREDGVAEA VEHALLDETI NRFLNDGARI SQLRVEIDDS
PQSVDYYSRH GFIRSVEAAS EGRVLLAGDR VAALGAIQAS LTGGDDQGTV GAVVMNLMAR
LLHDAGNLQG AVDAYLKALE LDPTRSEVFR GLGGAYQSQG QHQMAFASYQ QAINLAPWDL
LAYLKLGMLY EDLAVGKYEE AGDHAIRCFQ YYLQHSGSED TDVLTRLGNL QVMRLDPGSA
VETYRRALAV DKSLSNVWFN LANAYLKLGE EEEAATCLKE KLRLDPDPNA GVSARYLLAS
LEADPGRLTE SDQLAYAREL FDYYAPKYDD HMRKKLLYTG PRLLRKNMKE VYNATFQSFP
DEIQSAHNGD VLSYLNGSLD ILDLGCGTGL IGSWFKDYAR KLVGVDISPT MLDMATKKGC
YHELRRGDVR AYLAASEEQQ FDLVVAAETL QYLGPLETVV ADASKVLKPG GYFSFTVDRR
RTNEGEEQEG RDEQGHDEDD PEEGYSLKTD GTYAYSRGYL ERLARLGGYE IVVLKRHSTM
VQRGEAAPGY MGVFRKPE
//
