ID D7G844_ECTSI Unreviewed; 504 AA.
AC D7G844;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Prenylcysteine lyase domain-containing protein {ECO:0000259|Pfam:PF07156};
GN ORFNames=Esi_0087_0014 {ECO:0000313|EMBL:CBJ27907.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBJ27907.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBJ27907.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the prenylcysteine oxidase family.
CC {ECO:0000256|ARBA:ARBA00009967}.
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DR EMBL; FN649107; CBJ27907.1; -; Genomic_DNA.
DR AlphaFoldDB; D7G844; -.
DR STRING; 2880.D7G844; -.
DR EnsemblProtists; CBJ27907; CBJ27907; Esi_0087_0014.
DR eggNOG; ENOG502QSHJ; Eukaryota.
DR InParanoid; D7G844; -.
DR OMA; QMWVESI; -.
DR OrthoDB; 551774at2759; -.
DR Proteomes; UP000002630; Chromosome LG26.
DR GO; GO:0001735; F:prenylcysteine oxidase activity; IEA:InterPro.
DR GO; GO:0030328; P:prenylcysteine catabolic process; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR010795; Prenylcys_lyase.
DR InterPro; IPR017046; Prenylcysteine_Oxase.
DR PANTHER; PTHR15944; FARNESYLCYSTEINE LYASE; 1.
DR PANTHER; PTHR15944:SF0; PRENYLCYS_LYASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13450; NAD_binding_8; 1.
DR Pfam; PF07156; Prenylcys_lyase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..504
FT /note="Prenylcysteine lyase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003096244"
FT DOMAIN 125..476
FT /note="Prenylcysteine lyase"
FT /evidence="ECO:0000259|Pfam:PF07156"
SQ SEQUENCE 504 AA; 54126 MW; FDBA5AEE4F4B5170 CRC64;
MSRLGALLLV WLCHLLLTEG QEKVSIAVIG SGIGGSAASY FLREALDDDL HTKIVVFDSA
TKIGGRTAHY VHDGKVLESG ASVIYTGNAY LFNLTERVHL NKLDPSKQEG PNTGLWDGER
FVLKTTSSGI ANLARMVWRY GMSLLKMRSM VYEALAKFDR IYDLQADGRV FETPEDLWSE
VGLLGLARMT IAEYFEQRVG RAGSLVEVEL AHAANRVNYN QGNGLNALAG VVSLCPAVTG
DLFSVEGGNA RLSEELLGVS ASEVRLNTSV ARVVGSAKGG YSLYGQGEDT LGTFDAVVIA
TPIGLAGISL DMRGEDGSPE TPIQPLPVVK YQEVHTTFVR GVVDGAYFGL GKGEEVPNSV
LLTERAAGLA FSSLALKTWV GDPADGVGVY KLFSRQELWT GMLDSLFVQG SWEILHHREW
RAYPVLDPKK AFTRAKLFAG HPVWYVSSLE EGVSAMEVVV IAAKNAALGV AEALRSRNSQ
PGRVQEANLA ADTGSVDAAA SAEL
//
