ID D7G8C4_ECTSI Unreviewed; 651 AA.
AC D7G8C4;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Putative respiratory burst oxidase homolog {ECO:0000313|EMBL:CBJ27976.1};
DE EC=1.6.3.- {ECO:0000313|EMBL:CBJ27976.1};
GN Name=NOX {ECO:0000313|EMBL:CBJ27976.1};
GN ORFNames=Esi_0088_0069 {ECO:0000313|EMBL:CBJ27976.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBJ27976.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBJ27976.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
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DR EMBL; FN649117; CBJ27976.1; -; Genomic_DNA.
DR AlphaFoldDB; D7G8C4; -.
DR STRING; 2880.D7G8C4; -.
DR EnsemblProtists; CBJ27976; CBJ27976; Esi_0088_0069.
DR eggNOG; KOG0039; Eukaryota.
DR InParanoid; D7G8C4; -.
DR OrthoDB; 367877at2759; -.
DR Proteomes; UP000002630; Chromosome LG33.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR013121; Fe_red_NAD-bd_6.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR11972:SF69; METALLOREDUCTASE AIM14-RELATED; 1.
DR PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF08030; NAD_binding_6; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:CBJ27976.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 222..277
FT /note="FAD-binding 8"
FT /evidence="ECO:0000259|Pfam:PF08022"
FT DOMAIN 299..484
FT /note="Ferric reductase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF08030"
FT REGION 416..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 479..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 571..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..439
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..522
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..549
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 651 AA; 70505 MW; 7B8EF4033A37B21C CRC64;
MEPPVQGCGI MSSTTFLKLV TVLAMAYFGV KLWTLHYDPA SGRLCTFHDR HACVTSALSK
VLLTVSRMSA GALLPSMACC ILSKCYATRY FLHHSWLALV VSFEPAHELH TYFGSLTLLF
GVLHGLAHLA REVNEGHWNC FASSMGRSGF IALVLLFPIA VPMLLGRPKK LMTFEFRKAL
HMLFIPFMVA MCFHGKVLAV LAGILVAWYL VDRTYFTTRI GYQFKVGSYI QVNCPAISAK
EWHPFSMFPV PGPRPRGGFY VEAVGDWTQE LFRLSLDDPC MPLWITAAQP SVLEKSVYFE
NVIMVCTGAG ITPAICLADM LSKKKNVHLM WLSREAGMVA TFEKQLRRVN STVHLTGKPT
EKTKQRLTDL LAHSKAPPPA ETGSSCSDPT DLEAGFAAAR SRNDDFDDGA YGAGGDMEDL
GGCSSNRRNL SSAGGGMSGN RSSGGGGGGG KRLRRTPFGK PISLNFGRPD IEKFLTETIR
GSSSSQHEKW AATGGPPGKI VGAAAVGDSW QPQQNASKLR ASPPPSTGRH AEKERDYSDT
SSRDVRKKVL ARLNTNQRIS KRDLMSADLS VVPGKASPPR VPRSGRVTAA ASDMGSPDGV
GGGGGGASGA AWDARTWLVL YCGANAKVEE AVETACDDLC VTWRKEYFSA W
//
