ID D7K1V9_9BACE Unreviewed; 689 AA.
AC D7K1V9;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Subtilase family domain protein {ECO:0000313|EMBL:EFI40708.1};
GN ORFNames=HMPREF9010_01803 {ECO:0000313|EMBL:EFI40708.1};
OS Bacteroides sp. 3_1_23.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=457390 {ECO:0000313|EMBL:EFI40708.1, ECO:0000313|Proteomes:UP000003808};
RN [1] {ECO:0000313|EMBL:EFI40708.1, ECO:0000313|Proteomes:UP000003808}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3_1_23 {ECO:0000313|EMBL:EFI40708.1,
RC ECO:0000313|Proteomes:UP000003808};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Earl A., Feldgarden M., Gevers D., Young S.K., Zeng Q.,
RA Koehrsen M., Alvarado L., Berlin A., Bochicchio J., Borenstein D.,
RA Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J.,
RA Yandava C., Strauss J., Daigneault M., McDonald J., Ambrose C.E.,
RA Allen-Vercoe E., Haas B., Nusbaum C., Birren B.;
RT "The Genome Sequence of Bacteroides sp. strain 3_1_23.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
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DR EMBL; GG774949; EFI40708.1; -; Genomic_DNA.
DR RefSeq; WP_008648327.1; NZ_GG774949.1.
DR AlphaFoldDB; D7K1V9; -.
DR HOGENOM; CLU_014786_0_0_10; -.
DR Proteomes; UP000003808; Unassembled WGS sequence.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.1080; -; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR032304; Peptidase_S8_N.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PANTHER; PTHR42884:SF14; NEUROENDOCRINE CONVERTASE 1; 1.
DR PANTHER; PTHR42884; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR Pfam; PF16361; Peptidase_S8_N; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..689
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003099726"
FT DOMAIN 47..195
FT /note="Subtilase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16361"
FT DOMAIN 233..547
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT ACT_SITE 240
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 299
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 510
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 689 AA; 74097 MW; 51D18E0851A8F9AE CRC64;
MKRIYLILIA AVAITFASCS DQDMDAVKPD TGQGAPIIDL PEGATQGKIL VKFKPEAASF
LDAATTRSIG GALTRSGISD MDAVLQRIGI SELERIFPVD SRTEERTRKA GLNLWYIIHF
AEDTDLEQVA KDLSQVADVA KVQFTRAIQR SYDPNVRATV LTKQAMTRVV HTTRAVNTDA
NDPFFNLQWG CKNDGSILQN GEKNDKGDNV VPAVMGVDVN CGEAWKLCTG NPSIVVAVLD
EGVMYDHPDL EGNIWVNEDE TFASKEDADG NGYAGDRYGY NFTDDKGYIS YDDPNDTGHG
THVAGIISAV RNNGEGISGI AGGDKANNRG GVKIMSCQVF SGSKGCDLYQ EAKAVKYAAD
NGAVILQCSW GYNSGLSNPI SGYTPGFTSD KDWVDAAPLE KEAFDYFLHN AGSPNDVIDG
GIIVFAAGNE YAAMAGYPGA YPDYISVAAL AADGTPSCYS NYAMGVSIAA PGGDSDYHQS
SKGKIYSTLP PSANEDGGEN SHYGYMEGTS QACPHISGVA ALGLSYAAEL HRHFRADEFR
KMILESVNPV EPYFKETKVY WYTNASFGQI AAGQMEPAAY AGNMGTGLID AYKLLKAVEG
GGVEMTVPNM YVAVEATSKI NYSRYFKNGE NMTFTCTVDD NSIATLTTEN NITFTLKGLK
VGSTKATVKA SDGTKQDFFI TVRKNDSWM
//
