ID   D7KRN7_ARALL            Unreviewed;       703 AA.
AC   D7KRN7;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Lipase family protein {ECO:0000313|EMBL:EFH63774.1};
GN   ORFNames=ARALYDRAFT_476529 {ECO:0000313|EMBL:EFH63774.1};
OS   Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN   [1] {ECO:0000313|Proteomes:UP000008694}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX   PubMed=21478890; DOI=10.1038/ng.807;
RA   Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA   Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA   Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA   Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA   Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA   Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT   "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT   change.";
RL   Nat. Genet. 43:476-481(2011).
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DR   EMBL; GL348714; EFH63774.1; -; Genomic_DNA.
DR   RefSeq; XP_002887515.1; XM_002887469.1.
DR   AlphaFoldDB; D7KRN7; -.
DR   STRING; 81972.D7KRN7; -.
DR   ESTHER; arath-AT1G73920; Acidic_Lipase.
DR   EnsemblPlants; fgenesh2_kg.2__1659__AT1G73920.1; fgenesh2_kg.2__1659__AT1G73920.1; fgenesh2_kg.2__1659__AT1G73920.1.
DR   Gramene; fgenesh2_kg.2__1659__AT1G73920.1; fgenesh2_kg.2__1659__AT1G73920.1; fgenesh2_kg.2__1659__AT1G73920.1.
DR   eggNOG; KOG2624; Eukaryota.
DR   HOGENOM; CLU_015070_0_0_1; -.
DR   OrthoDB; 8619at2759; -.
DR   Proteomes; UP000008694; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR006693; AB_hydrolase_lipase.
DR   PANTHER; PTHR11005:SF169; ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN; 1.
DR   PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR   Pfam; PF04083; Abhydro_lipase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008694};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        132..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          297..351
FT                   /note="Partial AB-hydrolase lipase"
FT                   /evidence="ECO:0000259|Pfam:PF04083"
FT   REGION          91..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          165..195
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          247..282
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..180
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        181..195
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   703 AA;  79958 MW;  5EA23567B1D64C9E CRC64;
     MQRIVDNALA VTKESVKTVT YESLNNIARC INGVSALLLT LLPGKANILE GLHGWELRPT
     FRGPRLPRWM HNGVSSFNEF IHELSVDSDT SSLEYSSGED SDGPMPPSPS SQSSRLSWAS
     TSASSENHWT EWITFILWLL IFPLRILLWI PQYIMSLFLK RSSRTPASPR RHQHSCRHRI
     SKTNSSKDHD VPNRTTDRRR GVIEDLHLAI EIAIEAIFDF FHKATHLLLS PSEAFAILLS
     WFSSSSHSPK ENHGDVTDDG TVQTATLGDT DPSPTERPIE RPTRLYNSMN TDTRTCQDVI
     TELGYPYEAI RVVTSDGYVL VLERIPRRDA RKAVFLQHGV LDSSMGWVSN GVVGSPAFAA
     YDQGYDVFLG NFRGLVSRDH VNKNISSKEF WRYSINEHGT EDIPAMIEKI HEIKTTELKL
     YQPNIDDEES NQEEPYKLCA ICHSLGGAAI LMYVITRKIK EKPHRLSRLI LLSPAGFHED
     SNLGFTIVEY IFLFISPVLA RIVPAFYIPT RFFRMLLNKL ARDFHNYPAL GGLVQTLMSY
     VVGGDSSNWV GVLGLPHYNM NDMPAVSFRV AQHLAQIKHS GKFRMYDYGS RSANMEVYGS
     PEPLDLGESY KFIDVPVDLV AGRNDKVIRS SMVKKHYNVM RDAEVDVSFN EFEYAHLDFT
     FSHREELLRY VMSRLLLVKQ TPVQQRQTSQ KGMKLKKKKK EVQ
//