ID D7MNA2_ARALL Unreviewed; 642 AA.
AC D7MNA2;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 22-FEB-2023, entry version 53.
DE RecName: Full=MHD domain-containing protein {ECO:0000259|PROSITE:PS51072};
GN ORFNames=ARALYDRAFT_495846 {ECO:0000313|EMBL:EFH40777.1};
OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=81972 {ECO:0000313|Proteomes:UP000008694};
RN [1] {ECO:0000313|Proteomes:UP000008694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694};
RX PubMed=21478890; DOI=10.1038/ng.807;
RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M.,
RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G.,
RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K.,
RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J.,
RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y.,
RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.;
RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size
RT change.";
RL Nat. Genet. 43:476-481(2011).
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DR EMBL; GL348720; EFH40777.1; -; Genomic_DNA.
DR RefSeq; XP_002864518.1; XM_002864472.1.
DR AlphaFoldDB; D7MNA2; -.
DR STRING; 81972.D7MNA2; -.
DR EnsemblPlants; fgenesh2_kg.8__1662__AT5G57460.1; fgenesh2_kg.8__1662__AT5G57460.1; fgenesh2_kg.8__1662__AT5G57460.1.
DR Gramene; fgenesh2_kg.8__1662__AT5G57460.1; fgenesh2_kg.8__1662__AT5G57460.1; fgenesh2_kg.8__1662__AT5G57460.1.
DR eggNOG; KOG2398; Eukaryota.
DR HOGENOM; CLU_027682_0_0_1; -.
DR OrthoDB; 1207982at2759; -.
DR Proteomes; UP000008694; Unassembled WGS sequence.
DR GO; GO:0072583; P:clathrin-dependent endocytosis; IEA:EnsemblPlants.
DR GO; GO:0009555; P:pollen development; IEA:EnsemblPlants.
DR CDD; cd09257; AP_muniscins_like_MHD; 1.
DR InterPro; IPR036168; AP2_Mu_C_sf.
DR InterPro; IPR028565; MHD.
DR InterPro; IPR018808; Muniscin_C.
DR PANTHER; PTHR37769; OS08G0243900 PROTEIN; 1.
DR PANTHER; PTHR37769:SF1; OS08G0243900 PROTEIN; 1.
DR Pfam; PF10291; muHD; 1.
DR SUPFAM; SSF49447; Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; 1.
DR PROSITE; PS51072; MHD; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008694}.
FT DOMAIN 403..642
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
FT REGION 46..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 46..70
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 642 AA; 70223 MW; 52B165D7CBE60543 CRC64;
MSCLALALQP ANGSDILLQT REWFPPARAL IALSYFRQMR QALASSKQQH QQQSNQKQNQ
ASSSSSVADP DDATAAEFVG DDPLAASNGQ VIVGVESKYR VVYRLVNSIY ILGVTVADHD
NSINVFECIH IVNQAVSVIV TACRGVEVTP EKLGRKYAEV YMALDIVLRG VSNIRLAAML
GAMHGDGIAK MVHSALDTEN KIRGADSWMA VESHAAEHQA SVHAFSNARF ELPLETISAG
DEFAASLAPV VPESEQLKEE PEPENKDPFA ASETINKEKE LVGGFKKTKD PSSTDLTLAL
AGLEVTTLPP AEATQSTHIN VEGFEGQYGG IEFSNEQATI GETFESFSDA WGGGLDPSEF
MGPKKIQKKE GLGGLELLHT SDPKAVEGKD GGNLDNLVKK PEMKGPEMYI SEEIRTEFRE
SLLARVGVMG VIYLKTMPPK GSGEEKETEF SFRVEGTTAV KRFAMQSSRI SSLGNGLFHV
RTAPSEEPIP ILKYSLQPKL TPLPLRVRMV KRTSGTLLSL MIQYVSNPDL PQPLKNVDFI
LKLPVDPTLL KVSPKAILNR TDRELKWQIP EIPLKGSPGR LRARMPIDSD NSEEEPEIIC
YVKFSVQGNT SLSGISLRAA AEGNTDFYEV DHRYETGVYM CN
//
