ID   D7N7M8_9FIRM            Unreviewed;       227 AA.
AC   D7N7M8;
DT   10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT   10-AUG-2010, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=Transcriptional regulator, GntR family {ECO:0000313|EMBL:EFI41447.1};
GN   ORFNames=HMPREF0629_00066 {ECO:0000313|EMBL:EFI41447.1};
OS   Peptoniphilus sp. oral taxon 386 str. F0131.
OC   Bacteria; Bacillota; Tissierellia; Tissierellales; Peptoniphilaceae;
OC   Peptoniphilus.
OX   NCBI_TaxID=575609 {ECO:0000313|EMBL:EFI41447.1, ECO:0000313|Proteomes:UP000004712};
RN   [1] {ECO:0000313|EMBL:EFI41447.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0131 {ECO:0000313|EMBL:EFI41447.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA   Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA   Izard J., Baranova O.V., Blanton J.M., Tanner A.C., Dewhirst F.E., Haas B.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Peptoniphilus sp. oral taxon 386 strain F0131.";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL349422; EFI41447.1; -; Genomic_DNA.
DR   AlphaFoldDB; D7N7M8; -.
DR   STRING; 575609.HMPREF0629_00066; -.
DR   eggNOG; COG1802; Bacteria.
DR   HOGENOM; CLU_017584_5_1_9; -.
DR   Proteomes; UP000004712; Miscellaneous, Scaffold supercont1.1.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR011711; GntR_C.
DR   InterPro; IPR008920; TF_FadR/GntR_C.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR43537:SF5; GALACTONATE OPERON TRANSCRIPTIONAL REPRESSOR; 1.
DR   PANTHER; PTHR43537; TRANSCRIPTIONAL REGULATOR, GNTR FAMILY; 1.
DR   Pfam; PF07729; FCD; 1.
DR   Pfam; PF00392; GntR; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF48008; GntR ligand-binding domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004712};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          13..80
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50949"
SQ   SEQUENCE   227 AA;  26146 MW;  E22C690A9312758C CRC64;
     MNGEIMATQK EKKSLSNGVY DYLKTKILNN ELLPGDKLIE MEIAKELEVS RTPVREALAK
     LSKDGLAENF PRKSYIVSKI SMKDARDLYS VRTALEPMAV REIAEEGITN RTVILENIIS
     KMTRAYENGD LETVKEQIIE WNISLINLTQ NPILKDTLNI VNEKLYRFAN FIFRDEKNVK
     DVYTEINAIF SAIKNLDGEG AYNISYKYVS GIYPMLETQS DYKMFRF
//