ID D7N8H7_9FIRM Unreviewed; 586 AA.
AC D7N8H7;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Glutaconyl-CoA decarboxylase subunit alpha {ECO:0000313|EMBL:EFI41746.1};
DE EC=4.1.1.70 {ECO:0000313|EMBL:EFI41746.1};
GN Name=gcdA {ECO:0000313|EMBL:EFI41746.1};
GN ORFNames=HMPREF0629_00371 {ECO:0000313|EMBL:EFI41746.1};
OS Peptoniphilus sp. oral taxon 386 str. F0131.
OC Bacteria; Bacillota; Tissierellia; Tissierellales; Peptoniphilaceae;
OC Peptoniphilus.
OX NCBI_TaxID=575609 {ECO:0000313|EMBL:EFI41746.1, ECO:0000313|Proteomes:UP000004712};
RN [1] {ECO:0000313|EMBL:EFI41746.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0131 {ECO:0000313|EMBL:EFI41746.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Izard J., Baranova O.V., Blanton J.M., Tanner A.C., Dewhirst F.E., Haas B.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Peptoniphilus sp. oral taxon 386 strain F0131.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL349422; EFI41746.1; -; Genomic_DNA.
DR RefSeq; WP_009221685.1; NZ_GL349422.1.
DR AlphaFoldDB; D7N8H7; -.
DR STRING; 575609.HMPREF0629_00371; -.
DR eggNOG; COG4799; Bacteria.
DR HOGENOM; CLU_033980_0_0_9; -.
DR Proteomes; UP000004712; Miscellaneous, Scaffold supercont1.1.
DR GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.680; Single Helix bin; 1.
DR InterPro; IPR034733; AcCoA_carboxyl_beta.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011763; COA_CT_C.
DR InterPro; IPR011762; COA_CT_N.
DR InterPro; IPR045190; MCCB/AccD1-like.
DR PANTHER; PTHR22855; ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED; 1.
DR PANTHER; PTHR22855:SF13; METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL; 1.
DR Pfam; PF01039; Carboxyl_trans; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
DR PROSITE; PS50989; COA_CT_CTER; 1.
DR PROSITE; PS50980; COA_CT_NTER; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:EFI41746.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004712}.
FT DOMAIN 31..298
FT /note="CoA carboxyltransferase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50980"
FT DOMAIN 295..579
FT /note="CoA carboxyltransferase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50989"
SQ SEQUENCE 586 AA; 64370 MW; 612446E8F08A3F5F CRC64;
MSNYSMNVYF KNMSVIGSPL KATNEENIEA VRKVEEELAA RIAEVQAEGK PDEKINEGGE
WTALQRIAEL IDEGTWCPLN SLYNPENNSN GSTGIIKGLG KINDKWAVIV ASDNKKLAGA
WVPGQAENLL RASDTAKRLR IPLVYVLNCS GVKLDEQEKV YPNRRGGGTP FYRNSELNQL
GVPVIVGIYG TNPAGGGYHS ISPTILLAHK DANMAVGGAG ILGGMNPKGY IDEESANQIA
DATMNVKKTT PPGSVGVHFA QTGFFREVYV EEEGVIEAIR NYMDMLPSYD LDFFRVDDPK
APAFSANDLY SIVPMNPKRT YNIYDVISRL FDGSEFMEYK KGYGPEMVTG IAKVDGLLVG
VVANTQGFLM NYPEYKEKSI GIGGKLYRQG LIKMNEFVTL CARDRLPIVW IQDTTGIDVG
DDAEKAELLG LGQSLIYSIQ NSNIPQLEIT LRKGTAAAHY VLGGPQGNDT NAFSLGTATT
EINVMNGETA SVAMFSRRLA KDKKSGKDLQ PTIDKMNALI NAYVEKSRPQ FCAEAGLVDE
VVNMNLLRNY IVAFTQSVYQ NPESICPMHQ MLLPRVIRDF NNLYSK
//
