ID D7PPR1_9SECO Unreviewed; 1016 AA.
AC D7PPR1;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=RNA2 polyprotein {ECO:0000256|ARBA:ARBA00022361};
DE AltName: Full=Genome polyprotein M {ECO:0000256|ARBA:ARBA00032125};
DE AltName: Full=M RNA polyprotein {ECO:0000256|ARBA:ARBA00033402};
DE AltName: Full=Middle component RNA polyprotein {ECO:0000256|ARBA:ARBA00030233};
DE AltName: Full=P2 {ECO:0000256|ARBA:ARBA00031918};
OS Broad bean true mosaic virus.
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Picornavirales; Secoviridae; Comovirinae; Comovirus; Comovirus fabae.
OX NCBI_TaxID=649890 {ECO:0000313|EMBL:ADI60055.1, ECO:0000313|Proteomes:UP000201131};
RN [1] {ECO:0000313|EMBL:ADI60055.1, ECO:0000313|Proteomes:UP000201131}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EV-11 {ECO:0000313|EMBL:ADI60055.1};
RX PubMed=20496090; DOI=10.1007/s00705-010-0668-2;
RA Petrzik K.;
RT "Complete genome sequence of broad bean true mosaic virus.";
RL Arch. Virol. 155:1179-1181(2010).
CC -!- FUNCTION: Responsible for viral RNA2 accumulation. May function by
CC recruiting the RNA1-encoded polyprotein that contains the replication
CC protein to RNA2 and enable its replication.
CC {ECO:0000256|ARBA:ARBA00003642}.
CC -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma
CC {ECO:0000256|ARBA:ARBA00004621}.
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DR EMBL; GU810904; ADI60055.1; -; Genomic_RNA.
DR RefSeq; YP_008400127.1; NC_022006.1.
DR GeneID; 16536389; -.
DR KEGG; vg:16536389; -.
DR Proteomes; UP000201131; Genome.
DR GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0039617; C:T=3 icosahedral viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.20; -; 2.
DR InterPro; IPR003181; Como_LCP.
DR InterPro; IPR003182; RNA2_polyprotein.
DR InterPro; IPR029053; Viral_coat.
DR Pfam; PF02247; Como_LCP; 1.
DR Pfam; PF02248; Como_SCP; 1.
DR SUPFAM; SSF88633; Positive stranded ssRNA viruses; 3.
PE 4: Predicted;
KW Capsid protein {ECO:0000256|ARBA:ARBA00023060};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Host cell junction {ECO:0000256|ARBA:ARBA00023081};
KW Host-virus interaction {ECO:0000256|ARBA:ARBA00022463};
KW Inhibition of host innate immune response by virus
KW {ECO:0000256|ARBA:ARBA00022463}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Suppressor of RNA silencing {ECO:0000256|ARBA:ARBA00022463};
KW T=3 icosahedral capsid protein {ECO:0000256|ARBA:ARBA00023060};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00023031};
KW Viral immunoevasion {ECO:0000256|ARBA:ARBA00022463};
KW Viral movement protein {ECO:0000256|ARBA:ARBA00023031};
KW Virion {ECO:0000256|ARBA:ARBA00023060}.
FT TRANSMEM 50..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1016 AA; 112432 MW; B7E988353D21FA9C CRC64;
MFDWLQRHKR LNEINFVRQL QDSGHHFVSF QHSPVKYFEL ISFSNLIEKI LILQLVLLFI
LCDLCVGFLT SCVYFPVLTL CKMTTEIIQQ GIPAQLLEEK AAAFKRAKVA NKPLKDIIPS
SSQLYEKNFS FFERLKMCSN KRVLNLMELP AGSCAKYAHM KVEKLRALPV QTIDLPLVPR
EQVVGAENIY RSSNLGASAA ATAMHVGAME VIINSFASPS SDLMTAMMLV DTAHKRPENA
IRSIFIAPMC GGKPVRVVVF PNTLVPLNAD MNSRFKLVCS MPNCDFAEGA PIADISLNLV
GCVTGLERSY VPTPLLVEEY NKERGVIVDY LGKNTHALHL SNDVTPEQIG AMTFEFSHEG
PSELGVDVNG NCTFKRGEKL SYTIGGSSSG IRRALESSTE RHLDPRDDAV CHTFAQTSTD
LFRLSLNDTK EPEGSLLNTR FAQIKVRIPK SMEGGVVLAN KDFGSLIPVS NFRAYSSLAR
THRIEGEILC ISTINLPETT GCCLAICINS VSSGNSSTDI FNTGAQERVL WNPACSKNNV
FSFNPNPCST AWSLEFLKRT KLRVTVQCVS GWTTVPQTDL QMTMDWYVSN KSCVPRTYMC
AGGMQDVVMN RWMGKLVFPQ GIDLGLIRMP LAIGGGAGAE KAILMNMPHA TTSTWRYYRE
EFVFEVNKMS SPFIKSTICF FIGFGDLDET VTNLEDFPNK LVQFGEIAEK KELIFSHDEF
LTAWSTQVDP NKAIANDGCP YLYALVHDAT SSTIAGDFIL GVTLKTIKNF VGMGQNPGIQ
GARLLGAKAQ GPFSGVDQRF YSPVYKIRTP LNGVKGPGAS FSCDLLNGDV VTDVNKDWVI
QRFNSPVANL LKTAAWKKGT LHVKVSMLGS GTKHSDWQNV TQVILKNSLN TNSYAANTWS
IAEPGAFMFH FPLNIVGPNN GFEMRSSDWA SQTSWFLSFV ISNPEQCVFY EIDMAFGEDF
EVAGNNMMPP FDLDTSNTRS HSAIVRMLNK TSQPVELATA PQVSRTLRDL PQSMSK
//
