ID D7R4G7_CITFR Unreviewed; 387 AA.
AC D7R4G7;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=1,3-propanediol dehydrogenase {ECO:0000313|EMBL:ADG85685.1};
DE EC=1.1.1.202 {ECO:0000313|EMBL:HBH7042641.1, ECO:0000313|EMBL:SQA81576.1};
DE SubName: Full=Iron-containing alcohol dehydrogenase {ECO:0000313|EMBL:HAT3812520.1};
DE SubName: Full=Putative alcohol dehydrogenase {ECO:0000313|EMBL:SQA81576.1};
GN Name=dhaT {ECO:0000313|EMBL:ADG85685.1};
GN Synonyms=dhaT_1 {ECO:0000313|EMBL:SQA81576.1};
GN ORFNames=AI2602V1_0635 {ECO:0000313|EMBL:CAH3242852.1}, AN672_06540
GN {ECO:0000313|EMBL:KPR56444.1}, B9P89_01075
GN {ECO:0000313|EMBL:OYR07239.1}, I8618_001296
GN {ECO:0000313|EMBL:HAT3812520.1}, I9Y29_004134
GN {ECO:0000313|EMBL:HAT3899658.1}, KV121_002723
GN {ECO:0000313|EMBL:HBH7042641.1}, NCTC13639_00764
GN {ECO:0000313|EMBL:SQA81576.1};
OS Citrobacter freundii.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Citrobacter; Citrobacter freundii complex.
OX NCBI_TaxID=546 {ECO:0000313|EMBL:ADG85685.1};
RN [1] {ECO:0000313|EMBL:ADG85685.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 8090 {ECO:0000313|EMBL:ADG85685.1};
RA Lipinski D., Zeyland J., Przystalowska H., Slomski R.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000050520}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ST62:944112508 {ECO:0000313|Proteomes:UP000050520};
RA Osei Sekyere J., Govinden U., Essack S., Haldorsen B., Samuelsen O.,
RA Aasnaes B., Sundsfjord A.;
RT "Prevalence of NDMs in South Africa.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KPR56444.1, ECO:0000313|Proteomes:UP000050520}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ST62:944112508 {ECO:0000313|EMBL:KPR56444.1,
RC ECO:0000313|Proteomes:UP000050520};
RX PubMed=28636609;
RA Osei Sekyere J., Amoako D.G.;
RT "Genomic and phenotypic characterisation of fluoroquinolone resistance
RT mechanisms in Enterobacteriaceae in Durban, South Africa.";
RL PLoS ONE 12:E0178888-E0178888(2017).
RN [4] {ECO:0000313|EMBL:OYR07239.1, ECO:0000313|Proteomes:UP000215827}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C191 {ECO:0000313|EMBL:OYR07239.1,
RC ECO:0000313|Proteomes:UP000215827};
RA Zheng B.;
RT "Emergence of KPC-2-producing Citrobacter isolates from sediments of a
RT Chinese river.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:HAT3812520.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=91871 {ECO:0000313|EMBL:HBH7042641.1}, Citrobacter freundii
RC ARLG-4638 {ECO:0000313|EMBL:HAT3812520.1}, and O50
RC {ECO:0000313|EMBL:HAT3899658.1};
RX PubMed=30286803;
RA Souvorov A., Agarwala R., Lipman D.J.;
RT "SKESA: strategic k-mer extension for scrupulous assemblies.";
RL Genome Biol. 19:153-153(2018).
RN [6] {ECO:0000313|EMBL:SQA81576.1, ECO:0000313|Proteomes:UP000251140}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC13639 {ECO:0000313|EMBL:SQA81576.1,
RC ECO:0000313|Proteomes:UP000251140};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:HAT3899658.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=91871 {ECO:0000313|EMBL:HBH7042641.1}, Citrobacter freundii
RC ARLG-4638 {ECO:0000313|EMBL:HAT3812520.1}, and O50
RC {ECO:0000313|EMBL:HAT3899658.1};
RG NCBI Pathogen Detection Project;
RL Submitted (SEP-2020) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|EMBL:CAH3242852.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=112 {ECO:0000313|EMBL:CAH3242852.1};
RA Alioto T., Alioto T., Gomez Garrido J.;
RL Submitted (MAY-2022) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|ARBA:ARBA00001962};
CC -!- SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00007358}.
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DR EMBL; HM032027; ADG85685.1; -; Genomic_DNA.
DR EMBL; OW848788; CAH3242852.1; -; Genomic_DNA.
DR EMBL; DACSWJ010000004; HAT3812520.1; -; Genomic_DNA.
DR EMBL; DACSXJ010000034; HAT3899658.1; -; Genomic_DNA.
DR EMBL; DAESCB010000007; HBH7042641.1; -; Genomic_DNA.
DR EMBL; LJEB01000025; KPR56444.1; -; Genomic_DNA.
DR EMBL; NEFA01000001; OYR07239.1; -; Genomic_DNA.
DR EMBL; UAVQ01000004; SQA81576.1; -; Genomic_DNA.
DR RefSeq; WP_003024734.1; NZ_VWTQ01000008.1.
DR GeneID; 61126748; -.
DR PATRIC; fig|546.123.peg.2455; -.
DR OrthoDB; 9815791at2; -.
DR Proteomes; UP000050520; Unassembled WGS sequence.
DR Proteomes; UP000215827; Unassembled WGS sequence.
DR Proteomes; UP000251140; Unassembled WGS sequence.
DR Proteomes; UP000789662; Chromosome.
DR Proteomes; UP000855471; Unassembled WGS sequence.
DR Proteomes; UP000856779; Unassembled WGS sequence.
DR Proteomes; UP000885148; Unassembled WGS sequence.
DR GO; GO:0047516; F:1,3-propanediol dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd08188; PDDH; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR018211; ADH_Fe_CS.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF102; ALCOHOL DEHYDROGENASE 4; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR PROSITE; PS00913; ADH_IRON_1; 1.
DR PROSITE; PS00060; ADH_IRON_2; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:HBH7042641.1}.
FT DOMAIN 11..379
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 387 AA; 41452 MW; B80572AC487BD2D2 CRC64;
MSYRMFDYLV PNVNFFGPNA ISVVGERCKL LGGKKALLVT DKGLRAIKDG AVDKTLAHLR
EAGIDVVVFD GVEPNPKDTN VRDGLEVFRK EHCDIIVTVG GGSPHDCGKG IGIAATHEGD
LYSYAGIETL TNPLPPIVAV NTTAGTASEV TRHCVLTNTK TKVKFVIVSW RNLPSVSIND
PLLMLGKPAP LTAATGMDAL THAVEAYISK DANPVTDAAA IQAIRLIARN LRQAVALGSN
LKARENMAYA SLLAGMAFNN ANLGYVHAMA HQLGGLYDMP HGVANAVLLP HVARYNLIAN
PEKFADIAEF MGENTDGLST MDAAELAIHA IARLSADIGI PQHLRDLGVK EADFPYMAEM
ALKDGNAFSN PRKGNEKEIA EIFRQAF
//
