ID D7TSR0_VITVI Unreviewed; 384 AA.
AC D7TSR0;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=fructokinase {ECO:0000256|ARBA:ARBA00038887};
DE EC=2.7.1.4 {ECO:0000256|ARBA:ARBA00038887};
GN OrderedLocusNames=VIT_14s0006g01410 {ECO:0000313|EMBL:CBI33532.3};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CBI33532.3, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- FUNCTION: May play an important role in maintaining the flux of carbon
CC towards starch formation. {ECO:0000256|ARBA:ARBA00037195}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+);
CC Xref=Rhea:RHEA:16125, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:37721, ChEBI:CHEBI:61527, ChEBI:CHEBI:456216; EC=2.7.1.4;
CC Evidence={ECO:0000256|ARBA:ARBA00036647};
CC -!- PATHWAY: Glycan biosynthesis; starch biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004727}.
CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC {ECO:0000256|ARBA:ARBA00010688, ECO:0000256|RuleBase:RU003704}.
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DR EMBL; FN596245; CBI33532.3; -; Genomic_DNA.
DR RefSeq; XP_002274388.1; XM_002274352.3.
DR AlphaFoldDB; D7TSR0; -.
DR STRING; 29760.D7TSR0; -.
DR PaxDb; 29760-VIT_14s0006g01410-t01; -.
DR EnsemblPlants; Vitvi14g00950_t001; Vitvi14g00950_P001; Vitvi14g00950.
DR GeneID; 100258640; -.
DR Gramene; Vitvi14g00950_t001; Vitvi14g00950_P001; Vitvi14g00950.
DR KEGG; vvi:100258640; -.
DR eggNOG; KOG2855; Eukaryota.
DR HOGENOM; CLU_027634_6_1_1; -.
DR InParanoid; D7TSR0; -.
DR OMA; NWRPTFW; -.
DR OrthoDB; 5486729at2759; -.
DR Proteomes; UP000009183; Chromosome 14.
DR ExpressionAtlas; D7TSR0; baseline and differential.
DR GO; GO:0009507; C:chloroplast; IEA:EnsemblPlants.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0008865; F:fructokinase activity; IBA:GO_Central.
DR GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:EnsemblPlants.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:EnsemblPlants.
DR GO; GO:0006000; P:fructose metabolic process; IBA:GO_Central.
DR CDD; cd01167; bac_FRK; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR002139; Ribo/fructo_kinase.
DR InterPro; IPR029056; Ribokinase-like.
DR PANTHER; PTHR43085:SF61; FRUCTOKINASE-6, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR43085; HEXOKINASE FAMILY MEMBER; 1.
DR Pfam; PF00294; PfkB; 1.
DR PRINTS; PR00990; RIBOKINASE.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR PROSITE; PS00583; PFKB_KINASES_1; 1.
DR PROSITE; PS00584; PFKB_KINASES_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|RuleBase:RU003704};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003704}.
FT DOMAIN 65..371
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
SQ SEQUENCE 384 AA; 41234 MW; 770C98104122AEA2 CRC64;
MALLHSNGFC FTAVAFNHPP SVSHGPGTVK ASCSPFSSPS LPLLSLQRKA IPGDNGSPET
KENSLVVCFG EMLIDFVPTS NGLSLAEAPA FKKAPGGAPA NVAVGIARLG GSSAFIGKVG
EDEFGYMLAD ILKENNVNNE GMRFDPGART ALAFVTLRKD GEREFMFYRN PSADMLLQED
ELDFDLIRKA KIFHYGSISL ITEPCKSAHL AAAKAAKDAG VIVSYDPNLR LPLWPSADSA
REGILSIWNT ADIIKMSEEE ISFLTKGEDP YDDAVVRKFY HPNLKLLLVT EGPDGCRYYT
KDFSGRVKGL KVDAVDTTGA GDAFVAGILS QLAADLSLLQ EEDRLRDALK FANACGALTV
MERGAIPALP SREAVLNAML KLVT
//
