ID D8G7U3_9CYAN Unreviewed; 1811 AA.
AC D8G7U3;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 70.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=OSCI_3860035 {ECO:0000313|EMBL:CBN58683.1};
OS Kamptonema sp. PCC 6506.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Microcoleaceae; Kamptonema.
OX NCBI_TaxID=272129 {ECO:0000313|EMBL:CBN58683.1, ECO:0000313|Proteomes:UP000004532};
RN [1] {ECO:0000313|Proteomes:UP000004532}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 6506 {ECO:0000313|Proteomes:UP000004532};
RX PubMed=20675499; DOI=10.1128/JB.00704-10;
RA Mejean A., Mazmouz R., Mann S., Calteau A., Medigue C., Ploux O.;
RT "The genome sequence of the cyanobacterium Oscillatoria sp. PCC 6506
RT reveals several gene clusters responsible for the biosynthesis of toxins
RT and secondary metabolites.";
RL J. Bacteriol. 192:5264-5265(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CACA01000349; CBN58683.1; -; Genomic_DNA.
DR RefSeq; WP_007357860.1; NZ_CACA01000349.1.
DR OrthoDB; 517727at2; -.
DR Proteomes; UP000004532; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000004532};
KW Transferase {ECO:0000313|EMBL:CBN58683.1}.
FT DOMAIN 7..270
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1555..1809
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 1505..1536
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1811 AA; 203858 MW; E44F8FD812344AB8 CRC64;
MIAIPGVAVI ALIYESSKSL VYRGRIEQDN QPVILKLIKE EYPAPEELAR YRLEYEIIQN
LNLDSVVKAY SLQPFRNSLV MILEDFGGES LRIFMSSQKL TFFGFLTMAI KIAESLGEIH
AKNVIHKDIN PSNIVVNPTT GQLKIIDFSI ATELTRENTQ IKNPNILEGT LAYMSPEQTG
RMNRAVDYRT DFYSLGATFY ELLTGKLPFN TTDAMELVHC HIAKQPISPR EITPEIPQAL
ANIVMKLLAK TAEERYQSAW GIKADLESCL FQLQTSGYIA EFPLGSQDIS DKFQIPKKLY
GREKEIETLL AAFERVNTPY SESRGGEMML IAGYSGIGKS ALVRLLEKPI TNRHGYFIWG
KFDQYKRTTP YSAVVSAFSE LVRQLLTESE TQLTVWREKL RNAFGPNGQI IIDVIPEIEL
IVGQQSPVAE LGPTESQNRF NLVFQNFIRV FCQQEHPLVI FLDDLQWADS ATLKLIELIF
SDRETKYLFV IGAYRDNEVS PTHPLMMTLE NLRNQEAIIN EIILAPLDVE HVTNLIAETL
HSDKESVKPI AELVISKTDG NPFFVNQFLK TLYQENLLTF SPPQSGSKGE WQWNISDIEQ
CAITDNVVEL MIQKLKKLPE STQQILRLVA CLGNQFDLNT LSLIHEKEAS ETFHALLPAI
QEGLILPTSD LEAKSVELTH YPLLILNYKF LHDRVQQAAY TLIEDSQKKA VHLRIGRQIL
ANTPKEYRSE RIFELVDHLN VGRSLILDEE EQMELAILNL EAARKAKEAT AYFAAREYLT
ASMDGLTEDI WNADYDLAIA LHKERAEVEY LNGNFERSEE FINLTLKKTR SDLEKAEIYN
LLLVQYALRG KNEEAVKAGK NAITLLGIDL PEDGLDAAIG AEFAEAKASQ GNKEVAVLID
EPEMTLPEKK VALKLFNNLL PSAYFINPAL WTFSILKSVN LSLRYGHAPE SSFSYANYGI
LLNAVFGEYK SAYEFGLMAL KLTDKFGNLE LKGKVSTVFA NALSYWFQHL KESIPLNNEG
YKAALNSGDL QYAGYILNYK AIYSFFQGKN IGPLLTEVPS YLQFSLKTKN QMVTDTLNGL
QLILRNLSKL TSEKNDFSNE GITELEYIES CQEHQNFFTL CFYNIFKAQV FYCYGNLDEA
LKWVLSAEKQ LSFITGIFPV TEYNFYASLI FAALYSQVSE DEQKEYWAKL ESNQKQMKIW
AENSPENFLH KYLLVAAEMG RISGQESEAI DFYDRAISLA KKNEYIQHEA LANELAANFW
FSKDKPKYAN IHLRESYSAY KRWGAIRKVE DLEEKYPYLR DAVIANKTFK NSLNATIHTS
TGSDARALDL ATVMKASLAI SSEIFLDKLL ASLMKISIEN AGAQSGFLIL LSEGKLLISA
QASVTGGLAN KSGRTATEDV IVQQSTPLEE SQDLPVSVIN YVERTRSDVV LSNAAAEGRF
AADPYIVKQQ LKSLLCTPII NQGKLIGILY LENNLTTGVF TPDRLEVLRL LSSQVAISLE
NALLYASVEQ KVQERTQELN EKNGRLEQTL VELKVTQAQL IQTEKMSSLG QMVAGVAHEI
NNPVSFIYGN LTPASEYVKD LLNIIYLYQQ HYPTPAPEIQ SEIDRVELEF LVEDLEKLLD
SMKVGAERIR DIVLSLRNFS RLDEAEMKPV NIHSGIDSTV MLLQPRLRKE GGKLGIDVIK
EYVELPQITC YASQLNQVFM NILTNAIDAL ESVRSNSEDA EKKPMITIRT EVIGRNAIVR
IADNGPGMTP DVVHKIFDPF FTTKPVGSGT GLGLSISHSI VVKSHGGNLT CISAPFEGSE
FIIEIPLAPH Q
//
