ID D8IZY7_HERSS Unreviewed; 693 AA.
AC D8IZY7;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Type 3 secretion system secretin {ECO:0000256|HAMAP-Rule:MF_02219};
DE Short=T3SS secretin {ECO:0000256|HAMAP-Rule:MF_02219};
GN Name=hrcC {ECO:0000313|EMBL:ADJ62324.1};
GN Synonyms=sctC {ECO:0000256|HAMAP-Rule:MF_02219};
GN OrderedLocusNames=Hsero_0805 {ECO:0000313|EMBL:ADJ62324.1};
OS Herbaspirillum seropedicae (strain SmR1).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Herbaspirillum.
OX NCBI_TaxID=757424 {ECO:0000313|EMBL:ADJ62324.1, ECO:0000313|Proteomes:UP000000329};
RN [1] {ECO:0000313|EMBL:ADJ62324.1, ECO:0000313|Proteomes:UP000000329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SmR1 {ECO:0000313|EMBL:ADJ62324.1,
RC ECO:0000313|Proteomes:UP000000329};
RA Pedrosa F.O., Monteiro R.A., Wassem R., Cruz L.M., Ayub R.A., Colauto N.B.,
RA Fernandez M.A., Fungaro M.H.P., Grisard E.C., Hungria M., Madeira H.M.F.,
RA Nodari R.O., Osaku C.A., Petzl-Erler M.L., Terenzi H., Vieira L.G.E.,
RA Almeida M.I.M., Alves L.R., Arantes O.M.N., Balsanelli E., Barcellos F.G.,
RA Baura V.A., Binde D.R., Campo R.J., Chubatsu L.S., Chueire L.M.O.,
RA Ciferri R.R., Correa L.C., da Conceicao Silva J.L., Dabul A.N.G.,
RA Dambros B.P., Faoro H., Favetti A., Friedermann G., Furlaneto M.C.,
RA Gasques L.S., Gimenes C.C.T., Gioppo N.M.R., Glienke-Blanco C., Godoy L.P.,
RA Guerra M.P., Karp S., Kava-Cordeiro V., Margarido V.P., Mathioni S.M.,
RA Menck-Soares M.A., Murace N.K., Nicolas M.F., Oliveira C.E.C.,
RA Pagnan N.A.B., Pamphile J.A., Patussi E.V., Pereira L.F.P.,
RA Pereira-Ferrari L., Pinto F.G.S., Precoma C., Prioli A.J., Prioli S.M.A.P.,
RA Raittz R.T., Ramos H.J.O., Ribeiro E.M.S.F., Rigo L.U., Rocha C.L.M.S.C.,
RA Rocha S.N., Santos K., Satori D., Silva A.G., Simao R.C.G., Soares M.A.M.,
RA Souza E.M., Steffens M.B.R., Steindel M., Tadra-Sfeir M.Z., Takahashi E.K.,
RA Torres R.A., Valle J.S., Vernal J.I., Vilas-Boas L.A., Watanabe M.A.E.,
RA Weiss V.A., Yates M.A., Souza E.M.;
RT "The genome of Herbaspirillum seropedicae SmR1, an endophytic, nitrogen-
RT fixing, plant-growth promoting beta-Proteobacteria.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the type III secretion system (T3SS), also
CC called injectisome, which is used to inject bacterial effector proteins
CC into eukaryotic host cells. Forms a ring-shaped multimeric structure
CC with an apparent central pore in the outer membrane.
CC {ECO:0000256|HAMAP-Rule:MF_02219}.
CC -!- SUBUNIT: The core secretion machinery of the T3SS is composed of
CC approximately 20 different proteins, including cytoplasmic components,
CC a base, an export apparatus and a needle. This subunit is part of the
CC base, which anchors the injectisome in the bacterial cell envelope.
CC Forms a stable homooligomeric complex. {ECO:0000256|HAMAP-
CC Rule:MF_02219}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000256|HAMAP-
CC Rule:MF_02219, ECO:0000256|RuleBase:RU004004}.
CC -!- SIMILARITY: Belongs to the bacterial secretin family. T3SS SctC
CC subfamily. {ECO:0000256|HAMAP-Rule:MF_02219}.
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DR EMBL; CP002039; ADJ62324.1; -; Genomic_DNA.
DR RefSeq; WP_013232841.1; NC_014323.1.
DR AlphaFoldDB; D8IZY7; -.
DR STRING; 757424.Hsero_0805; -.
DR KEGG; hse:Hsero_0805; -.
DR eggNOG; COG1450; Bacteria.
DR HOGENOM; CLU_022474_1_0_4; -.
DR OrthoDB; 9779724at2; -.
DR Proteomes; UP000000329; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0030257; C:type III protein secretion system complex; IEA:UniProtKB-UniRule.
DR GO; GO:0030254; P:protein secretion by the type III secretion system; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1370.120; -; 2.
DR Gene3D; 3.55.50.30; -; 1.
DR HAMAP; MF_02219; Type_III_secretin; 1.
DR InterPro; IPR005644; NolW-like.
DR InterPro; IPR038591; NolW-like_sf.
DR InterPro; IPR004846; T2SS/T3SS_dom.
DR InterPro; IPR003522; T3SS_OM_pore_YscC.
DR NCBIfam; TIGR02516; type_III_yscC; 1.
DR PANTHER; PTHR30332; PROBABLE GENERAL SECRETION PATHWAY PROTEIN D; 1.
DR PANTHER; PTHR30332:SF5; SPI-1 TYPE 3 SECRETION SYSTEM SECRETIN; 1.
DR Pfam; PF00263; Secretin; 1.
DR Pfam; PF03958; Secretin_N; 1.
DR PRINTS; PR01337; TYPE3OMGPROT.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|HAMAP-Rule:MF_02219};
KW Membrane {ECO:0000256|HAMAP-Rule:MF_02219};
KW Protein transport {ECO:0000256|HAMAP-Rule:MF_02219};
KW Reference proteome {ECO:0000313|Proteomes:UP000000329};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|HAMAP-Rule:MF_02219};
KW Translocation {ECO:0000256|HAMAP-Rule:MF_02219};
KW Transmembrane {ECO:0000313|EMBL:ADJ62324.1};
KW Transport {ECO:0000256|HAMAP-Rule:MF_02219, ECO:0000256|RuleBase:RU004004}.
FT DOMAIN 184..338
FT /note="NolW-like"
FT /evidence="ECO:0000259|Pfam:PF03958"
FT DOMAIN 404..574
FT /note="Type II/III secretion system secretin-like"
FT /evidence="ECO:0000259|Pfam:PF00263"
FT REGION 224..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 479..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 593..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..251
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..501
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..626
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 693 AA; 72741 MW; F91E5DFD6E21464F CRC64;
MNAREIIKSW GMGLLLAGLL LWGTTLHAAV PPAWKDGGFS ISANGMTVRG VLEEFSRTYG
VRLNLSADGA QIVKGRLKAD NGVEFLNRLT GAHRMRWFVY NDTLYVTPAA DNTSSRMQVG
EDAVMDAKAA LVGLGLFDER FGWGELPDEG VVIVSGPRVY VDLAREVLMP VGKKEKLRGR
QIMLFRLKYA SANDRVINSR GKAETIPGIK TILTNLLMGA HGGEKVTGNN RFDADSRKRS
RTGRIARADG DEAAAESSGQ RFTPLFSPPG GNGRNQLMAG AGNDNAGAGA SAAQEAEGKQ
PPRIEADSSL NAIMIYDDIA KRDMYAALIN QLDVKPQQVE IEALIVDIDR SRLAEMGVEW
GARAGVVNTT VNGTTTQSSG TDLPLPGATL LISDAARFYA RLKAMESNGE ARVLATPTVL
TLDNVAAVLD LSQSAYVSLI GERVADMSDI TAGTMLRVIP RIIDDGGQTR VRLEVDIEDG
SLNNGNNDSG SNSSRGTGAS TIAASVTRST INTQAIIDAQ QTLMIGGYRA ESLIRNKQKV
PLLGDLPVVG GLFRSESRSN STRERLFLIT PRITSFDGTR LASNAAAARP NSASAGAAGA
STAAPLPPNA PGMPSAPVPA PNQTSLPLPA PAGAATSGGA PPVMLPLPVG AATPRAEEPA
TAAAPSGGSL MGVRMPLRKT ANRCARPGSV GML
//
