ID D8JTU1_HYPDA Unreviewed; 407 AA.
AC D8JTU1;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit {ECO:0000313|EMBL:ADJ24489.1};
DE EC=2.1.1.132 {ECO:0000313|EMBL:ADJ24489.1};
GN OrderedLocusNames=Hden_2693 {ECO:0000313|EMBL:ADJ24489.1};
OS Hyphomicrobium denitrificans (strain ATCC 51888 / DSM 1869 / NCIMB 11706 /
OS TK 0415).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Hyphomicrobiaceae; Hyphomicrobium.
OX NCBI_TaxID=582899 {ECO:0000313|EMBL:ADJ24489.1, ECO:0000313|Proteomes:UP000002033};
RN [1] {ECO:0000313|Proteomes:UP000002033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51888 / DSM 1869 / NCIB 11706 / TK 0415
RC {ECO:0000313|Proteomes:UP000002033};
RX PubMed=21705585; DOI=10.1128/JB.05453-11;
RG US DOE Joint Genome Institute;
RA Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.;
RT "Genome sequences of eight morphologically diverse alphaproteobacteria.";
RL J. Bacteriol. 193:4567-4568(2011).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
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DR EMBL; CP002083; ADJ24489.1; -; Genomic_DNA.
DR RefSeq; WP_013216648.1; NC_014313.1.
DR AlphaFoldDB; D8JTU1; -.
DR STRING; 582899.Hden_2693; -.
DR KEGG; hdn:Hden_2693; -.
DR eggNOG; COG2241; Bacteria.
DR eggNOG; COG2242; Bacteria.
DR HOGENOM; CLU_031955_0_0_5; -.
DR OrthoDB; 9787825at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000002033; Chromosome.
DR GO; GO:0046025; F:precorrin-6Y C5,15-methyltransferase (decarboxylating) activity; IEA:UniProtKB-EC.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11644; Precorrin-6Y-MT; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR012818; CbiE.
DR InterPro; IPR006365; Cbl_synth_CobL.
DR InterPro; IPR014008; Cbl_synth_MTase_CbiT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR02467; CbiE; 1.
DR NCBIfam; TIGR02469; CbiT; 1.
DR PANTHER; PTHR43182; COBALT-PRECORRIN-6B C(15)-METHYLTRANSFERASE (DECARBOXYLATING); 1.
DR PANTHER; PTHR43182:SF1; COBALT-PRECORRIN-7 C(5)-METHYLTRANSFERASE; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR PIRSF; PIRSF036428; CobL; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ADJ24489.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002033};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ADJ24489.1}.
FT DOMAIN 6..192
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 407 AA; 42881 MW; A86A90F5DEF0515E CRC64;
MSGRWLSIIG IGEDGRAGLG SAANALIDAA ELIVGGERHL ALVGDTRGEK MQWRTPLDAT
SQDILARRGK PVAVLVSGDP FWFGAGVTLT RAIPIDEMLV VTSPSSFSLA ASRLGWALQD
TVTLGLNMRG LTPLLRRHVH HGRRILALAL NGETPGEVAK LLTSAGYGPS TITVLEALGG
PRERIRSTTA EAFALTDVDP LNVIAIDVVA GPEAMPIPYA AGLPDTYFEN DGQLTKREVR
AVTLSSLQPG AGELLWDIGA GSGSVGIEWM LAHPANRAIG IERDETRAAR AVRNAVTLGV
PQLDIRKGAA PDALDGLPSP DAIFIGCGSA DRDLIGTCWN ALKPGGRIVV NSVTLESELA
VLAAYHAHGG TLTRFAVERA EPLGKRMTWR PALPIIQWVS RKPGAGA
//
