ID D8LSY2_ECTSI Unreviewed; 593 AA.
AC D8LSY2;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Heat shock protein 40 like protein/ DnaJ domain containing protein {ECO:0000313|EMBL:CBN77909.1};
GN ORFNames=Esi_0077_0101 {ECO:0000313|EMBL:CBN77909.1};
OS Ectocarpus siliculosus (Brown alga) (Conferva siliculosa).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC Ectocarpales; Ectocarpaceae; Ectocarpus.
OX NCBI_TaxID=2880 {ECO:0000313|EMBL:CBN77909.1, ECO:0000313|Proteomes:UP000002630};
RN [1] {ECO:0000313|EMBL:CBN77909.1, ECO:0000313|Proteomes:UP000002630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ec32 / CCAP1310/4 {ECO:0000313|Proteomes:UP000002630};
RX PubMed=20520714; DOI=10.1038/nature09016;
RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G.,
RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B.,
RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., Brownlee C.,
RA Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., Collen J., Corre E.,
RA Da Silva C., Delage L., Delaroque N., Dittami S.M., Doulbeau S., Elias M.,
RA Farnham G., Gachon C.M., Gschloessl B., Heesch S., Jabbari K., Jubin C.,
RA Kawai H., Kimura K., Kloareg B., Kupper F.C., Lang D., Le Bail A.,
RA Leblanc C., Lerouge P., Lohr M., Lopez P.J., Martens C., Maumus F.,
RA Michel G., Miranda-Saavedra D., Morales J., Moreau H., Motomura T.,
RA Nagasato C., Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F.,
RA Pommier C., Potin P., Poulain J., Quesneville H., Read B., Rensing S.A.,
RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., Segurens B.,
RA Strittmatter M., Tonon T., Tregear J.W., Valentin K., von Dassow P.,
RA Yamagishi T., Van de Peer Y., Wincker P.;
RT "The Ectocarpus genome and the independent evolution of multicellularity in
RT brown algae.";
RL Nature 465:617-621(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FN649003; CBN77909.1; -; Genomic_DNA.
DR AlphaFoldDB; D8LSY2; -.
DR STRING; 2880.D8LSY2; -.
DR EnsemblProtists; CBN77909; CBN77909; Esi_0077_0101.
DR eggNOG; KOG0721; Eukaryota.
DR InParanoid; D8LSY2; -.
DR OrthoDB; 1605at2759; -.
DR Proteomes; UP000002630; Unplaced LGUn.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd06257; DnaJ; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.10.287.110; DnaJ domain; 1.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR036869; J_dom_sf.
DR InterPro; IPR004179; Sec63-dom.
DR PANTHER; PTHR24075; SEC63 DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR24075:SF0; TRANSLOCATION PROTEIN SEC63 HOMOLOG; 1.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF02889; Sec63; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SUPFAM; SSF46565; Chaperone J-domain; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
PE 4: Predicted;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000002630};
KW Stress response {ECO:0000313|EMBL:CBN77909.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 116..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..87
FT /note="J"
FT /evidence="ECO:0000259|PROSITE:PS50076"
FT REGION 211..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 330..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..234
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..308
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 593 AA; 63131 MW; E508E14544101251 CRC64;
MISYAFNQVA SSMQTEAEHF DPYHILDLPS RANATVIKSH YRRLSLKHHP DKNPGNRREA
NKKFTQVAKA YKALSDPEAR RNWEQYGHPD GYQPWTFDLA LPAWLRPGKD TDNGTLVLYG
LGYMVVLLGF VLGAKVTLDL LDPAGGGKQP DFEVTDEDVK ALLSNLDDTS STADVLECLA
ACPQLCSEER RVLAGEMEAI TDPLRDWLLE REGGAPPLRG PRSSSPPPPP QAAAAAAAAK
PASRKGKGKG KGKNGSGKSK GGESPASGEE QAPAAAAGAG TKGEVDGEFF TQGRRGEGNR
RTARESPELS RVVAHNLVVM LSALHRAPTP DAAVDGGVAV APGGGENGDD GDDDEGSAGG
VSTAGGGGKG ARLLSAVSVG GRLAREQDLV FGLAEPLLDA CMQVAARRAS PQLLGTVVET
KAMLRRRLWS SEDPAALKRQ REEADLDLDA AVPSIKVKSV AVETWGESQV AVGDTVTATI
TIAREHAPEY QGLRRRRPEA GSLIAKGEPW WVMLAGGKGG SSLIRVTPML VENLGSGIAE
CKMKFQAPTR PGFVDLTVFV KSPVFVGVDC ESTARFRVWR HDELKEDDDA GDW
//
