ID D8LYW3_BLAHO Unreviewed; 1000 AA.
AC D8LYW3;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=Cation-transporting P-type ATPase N-terminal domain-containing protein {ECO:0000259|SMART:SM00831};
GN ORFNames=GSBLH_T00001230001 {ECO:0000313|EMBL:CBK21002.2};
OS Blastocystis hominis.
OC Eukaryota; Sar; Stramenopiles; Bigyra; Opalozoa; Opalinata; Blastocystidae;
OC Blastocystis.
OX NCBI_TaxID=12968 {ECO:0000313|EMBL:CBK21002.2};
RN [1] {ECO:0000313|EMBL:CBK21002.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Singapore isolate B {ECO:0000313|EMBL:CBK21002.2};
RA Wincker P.;
RT "Sequencing and annotation of the Blastocystis hominis genome.";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FN668640; CBK21002.2; -; Genomic_DNA.
DR RefSeq; XP_012895050.1; XM_013039596.1.
DR AlphaFoldDB; D8LYW3; -.
DR EnsemblProtists; CBK21002; CBK21002; GSBLH_T00001230001.
DR GeneID; 24918503; -.
DR InParanoid; D8LYW3; -.
DR OMA; PLWNNMM; -.
DR OrthoDB; 203629at2759; -.
DR Proteomes; UP000008312; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF4; CALCIUM-TRANSPORTING ATPASE 1, ENDOPLASMIC RETICULUM-TYPE-RELATED; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008312};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 41..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 743..766
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 817..840
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 925..944
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..58
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
SQ SEQUENCE 1000 AA; 109810 MW; CACEEBDBBBDF7B32 CRC64;
MDDGLTDEEV LKRQSVYGLN ALAEEPPTPL WKLILEQFED YLVQILLVSA VLSFVLAFFE
NGGESSVTAF VEPFVILLIL ILNAIVGVWQ ENNAESALNA LKKMQSEKAR CIRNGVVNPN
LPAEQLVPGD IIRLNVGDKV PADCRILSLK TATLRVEESA LTGESRTVLK NPDVCTTVDA
GLSEKVNMLF AGTTIANGLC KALVVRTGMN TEIGKIQRAV MDAREDEEKT PLGQKIDEFG
ELLGKVIMWI CVIVWIMNFH QFSDPEFGGF FRGCIYYLKV AVALGVAAIP EGLPAVITLC
LSLGTRSMAR RNCIVRKLPS VETLGCTTVI CSDKTGTLTT NEMTVVTVST FHATGEACER
SVSGISYNPE GKVEGVDRLE ASQRALCDVA KVCAFCNETT VTWNDATQKY EAVGEPTEAA
LRILVEKLGF PEELLGSDHC VDSPVTQRCN DLWATLYSVN GCLEFSRTRK SMSVLVSKRP
VANELLVKGA PELLLQRCRW LCTEEGNVVP LTESMRQRCL EHLEQMSRRS LRCLALAGKH
EEGPLRSYDG PQHPAHAMLA DVEAYEAIEQ DLCLFGMVGI KDPARVEVRD SIALCKKAGI
RVFMITGDNK LTAESIARDV GILQPGEEAE ASFEAREFMK LPRERQLRIL AGHGGRVFAR
SEPVHKKELI SLLRQMGEIT AMTGDGVNDA PALQQADIGV AMGVSGTEVA KEASDMVLVD
DNFRTIVAAI EEGRSIYQNM KAFIRYLISS NIGEVASIFF TAMLGIPEGL SPVQLLWVNL
VTDGPPATAL GFNPPEPDIM ARPPRARDEG LITPFVFFRY VVIGLYVGVA TVGIFVYWYV
LDRAPDAHPL VSLAQLMGHG KCRAWTEFSL DGWGGFAQPC DYFEKGKVVA STLSLTVLVT
IEMFNALNAL SEDCSLLVVP PHRNLYLVAA ILASFVAHFA ILYIPPLAKV FSVAPLTLHD
WKLVLAFSFP VILIDEVLKA VSRAITRYKE EKLLQKEKEE
//
