ID D8MTA2_ERWBE Unreviewed; 692 AA.
AC D8MTA2;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093,
GN ECO:0000313|EMBL:CAX60059.1};
GN OrderedLocusNames=EbC_25280 {ECO:0000313|EMBL:CAX60059.1};
OS Erwinia billingiae (strain Eb661).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=634500 {ECO:0000313|Proteomes:UP000008793};
RN [1] {ECO:0000313|EMBL:CAX60059.1, ECO:0000313|Proteomes:UP000008793}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Eb661 {ECO:0000313|EMBL:CAX60059.1,
RC ECO:0000313|Proteomes:UP000008793};
RX PubMed=20565991; DOI=10.1186/1471-2164-11-393;
RA Kube M., Migdoll A.M., Gehring I., Heitmann K., Mayer Y., Kuhl H.,
RA Knaust F., Geider K., Reinhardt R.;
RT "Genome comparison of the epiphytic bacteria Erwinia billingiae and E.
RT tasmaniensis with the pear pathogen E. pyrifoliae.";
RL BMC Genomics 11:393-393(2010).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; FP236843; CAX60059.1; -; Genomic_DNA.
DR RefSeq; WP_013202545.1; NC_014306.1.
DR AlphaFoldDB; D8MTA2; -.
DR STRING; 634500.EbC_25280; -.
DR KEGG; ebi:EbC_25280; -.
DR eggNOG; COG1298; Bacteria.
DR HOGENOM; CLU_015346_3_0_6; -.
DR Proteomes; UP000008793; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:CAX60059.1};
KW Cilium {ECO:0000313|EMBL:CAX60059.1};
KW Flagellum {ECO:0000313|EMBL:CAX60059.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000008793};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 45..64
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 116..139
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 208..230
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 250..272
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 692 AA; 74508 MW; 5B3AA3BCB996BBF2 CRC64;
MANLAAILRL PNFKDTQWQV MAGPVLILMI LSMMVLPLPP FILDLLFTFN IALSIMVLLV
AMFTQKTLEF AAFPTILLFS TLLRLALNVA STRIILMEGH TGAGAAGQVV EAFGHFLVGG
NFAIGIVVFI ILVIINFMVI TKGAGRIAEV GARFVLDGMP GKQMAIDADL NAGLIGEEEA
KKRRSDVTQE ADFYGSMDGA SKFVRGDAIA GIMIMVINVV GGLLVGVIQH GMDVGHAAES
YTLLTIGDGL VAQIPALVIS TAAGVIVTRV GTDQDVGEQM VTQLFKNPRV MMLSAGVLGL
LGLVPGMPNL VFLLFTAALL GLAWYLRGKE TKPKAAAPAP TKQVEASSNT EASWGDVQLE
DSLGMEVGYR LIPMVDHQQD GELLGRIRSI RKKFAQEMGF LPPVVHIRDN MDLPPARYRI
LMKGVEIGSG DAYPGRWMAI NPGTAAGTLP GEPTVDPAFG LAATWIDSAL KEQAQIQGFT
VVEASTVVAT HLNHLIGQYA SELFGRQESQ QLLDRVTQEM PKLTEDLIPG VISLTTLHKV
LQNLLAERVS IRDMRTIIET LAEHAAVQTD PHELTSVVRV ALGRAITQQW FPGTGEVQVI
GLDTTLERLL LQALQGGGGL EPGLADRLMA QAQGALDHQE SLGAPPVLLV NHPLRALLAR
FLRRNMPQLM VISNLELSDN RNIRMTSTIG GH
//
