ID D8MUA6_ERWBE Unreviewed; 356 AA.
AC D8MUA6;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Lactose operon repressor {ECO:0000313|EMBL:CAX60413.1};
GN Name=lacI {ECO:0000313|EMBL:CAX60413.1};
GN OrderedLocusNames=EbC_28820 {ECO:0000313|EMBL:CAX60413.1};
OS Erwinia billingiae (strain Eb661).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=634500 {ECO:0000313|Proteomes:UP000008793};
RN [1] {ECO:0000313|EMBL:CAX60413.1, ECO:0000313|Proteomes:UP000008793}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Eb661 {ECO:0000313|EMBL:CAX60413.1,
RC ECO:0000313|Proteomes:UP000008793};
RX PubMed=20565991; DOI=10.1186/1471-2164-11-393;
RA Kube M., Migdoll A.M., Gehring I., Heitmann K., Mayer Y., Kuhl H.,
RA Knaust F., Geider K., Reinhardt R.;
RT "Genome comparison of the epiphytic bacteria Erwinia billingiae and E.
RT tasmaniensis with the pear pathogen E. pyrifoliae.";
RL BMC Genomics 11:393-393(2010).
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DR EMBL; FP236843; CAX60413.1; -; Genomic_DNA.
DR RefSeq; WP_013202898.1; NC_014306.1.
DR AlphaFoldDB; D8MUA6; -.
DR STRING; 634500.EbC_28820; -.
DR KEGG; ebi:EbC_28820; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_4_6; -.
DR Proteomes; UP000008793; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01574; PBP1_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF143; LACTOSE OPERON REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000008793};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 6..60
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 329..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..346
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 38020 MW; ED37B1DEA0FE815C CRC64;
MKPRSVTLDD VAAAAGVSYQ TVSRVLNHSA SVAEKTRLKV EAAMVALNYV PNRVAQQLAG
KHSRTLGLAT SDLALLAPAQ MASAIQQRAT ALGYRLVIAM SGAKGADVAV QELLAQRVDA
LLVNLPLDNA SASHIAALTR PLPGLFLDVP DDAPVPACQY SAETGARQGI EHLLALGHRE
IALLNGPKAS VAAASRHQTW LRVLAENQLT PHRELTGDWS AESGYQATLS LLGSALPTAL
LVANDQMALG ALRALHQAGL QIPAEISVVG YDDTAESAWY QPPLTTVRQD IKQLGERSVD
WLVQTLNEEQ SPALMRPFAT RLMIRETTAA PPQQRVNAQA MSGKRQQPAE KTKGDR
//
