ID D8P6M0_RALSL Unreviewed; 435 AA.
AC D8P6M0;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Putative multidrug resistance protein mdtA (Multidrug transporter mdtA) {ECO:0000313|EMBL:CBJ54556.1};
GN ORFNames=RCFBP_mp30476 {ECO:0000313|EMBL:CBJ54556.1};
OS Ralstonia solanacearum CFBP2957.
OG Plasmid RCFBPv3_mp {ECO:0000313|EMBL:CBJ54556.1}.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=859656 {ECO:0000313|EMBL:CBJ54556.1};
RN [1] {ECO:0000313|EMBL:CBJ54556.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFBP2957 {ECO:0000313|EMBL:CBJ54556.1};
RC PLASMID=RCFBPv3_mp {ECO:0000313|EMBL:CBJ54556.1};
RX PubMed=20550686; DOI=10.1186/1471-2164-11-379;
RA Remenant B., Coupat-Goutaland B., Guidot A., Cellier G., Wicker E.,
RA Allen C., Fegan M., Pruvost O., Elbaz M., Calteau A., Salvignol G.,
RA Mornico D., Mangenot S., Barbe V., Medigue C., Prior P.;
RT "Genomes of three tomato pathogens within the Ralstonia solanacearum
RT species complex reveal significant evolutionary divergence.";
RL BMC Genomics 11:379-379(2010).
RN [2] {ECO:0000313|EMBL:CBJ54556.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CFBP2957 {ECO:0000313|EMBL:CBJ54556.1};
RC PLASMID=RCFBPv3_mp {ECO:0000313|EMBL:CBJ54556.1};
RA Genoscope - CEA;
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; FP885907; CBJ54556.1; -; Genomic_DNA.
DR AlphaFoldDB; D8P6M0; -.
DR PATRIC; fig|859656.5.peg.4900; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR PANTHER; PTHR30469:SF37; RAGD PROTEIN; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Plasmid {ECO:0000313|EMBL:CBJ54556.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 55..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 122..338
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 14..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 197..224
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 435 AA; 46744 MW; 82E285D96590670E CRC64;
MPAGVALIYG EAKDMSDQTS GTHSGHLAEG PPHHVVTVDP IEPVDRPRAM RRARWVLIVV
AVLLALGAVR TLVGRYYNAH ALEHQMASQS TRYVNTIVPR PAAAGRELTL PGTLQGFVES
PIYARTNGYV LRWFKDIGAH VEKGEVLALL DTPEVDQELN QALAARNQTA ARRALAQTSL
ARWQSLRQKD AVSQQELDER TSAANQAQAD LAAAEANVRR LQELQGFRRI VAPFAGVVTK
RNVDVGTLVN AGNAGTNREL FTLAQTDPLR IYLYVPQAYS QQVKAGQDVA VTLAELPGQV
FHGAVARMSS AIDPTTRTMQ VEVSLPNKEG RLLPGAYVQV QIAGKAADDP PTAFVVPTNT
LLFRKEGPRI AVAENGRVNL RPVTIGRDYG RTVEILSGLK AGDALILNPA DSIEQGEAIT
VTPASAPAAP APRAS
//
