ID D8QB49_SCHCM Unreviewed; 435 AA.
AC D8QB49;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=G-protein alpha subunit {ECO:0008006|Google:ProtNLM};
GN ORFNames=SCHCODRAFT_257879 {ECO:0000313|EMBL:EFI94696.1};
OS Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX NCBI_TaxID=578458 {ECO:0000313|Proteomes:UP000007431};
RN [1] {ECO:0000313|EMBL:EFI94696.1, ECO:0000313|Proteomes:UP000007431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H4-8 / FGSC 9210 {ECO:0000313|Proteomes:UP000007431};
RX PubMed=20622885; DOI=10.1038/nbt.1643;
RA Ohm R.A., de Jong J.F., Lugones L.G., Aerts A., Kothe E., Stajich J.E.,
RA de Vries R.P., Record E., Levasseur A., Baker S.E., Bartholomew K.A.,
RA Coutinho P.M., Erdmann S., Fowler T.J., Gathman A.C., Lombard V.,
RA Henrissat B., Knabe N., Kuees U., Lilly W.W., Lindquist E., Lucas S.,
RA Magnuson J.K., Piumi F., Raudaskoski M., Salamov A., Schmutz J.,
RA Schwarze F.W.M.R., vanKuyk P.A., Horton J.S., Grigoriev I.V.,
RA Woesten H.A.B.;
RT "Genome sequence of the model mushroom Schizophyllum commune.";
RL Nat. Biotechnol. 28:957-963(2010).
CC -!- SIMILARITY: Belongs to the G-alpha family.
CC {ECO:0000256|ARBA:ARBA00005804}.
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DR EMBL; GL377309; EFI94696.1; -; Genomic_DNA.
DR RefSeq; XP_003029599.1; XM_003029553.1.
DR AlphaFoldDB; D8QB49; -.
DR STRING; 578458.D8QB49; -.
DR GeneID; 9594348; -.
DR KEGG; scm:SCHCO_02509801; -.
DR VEuPathDB; FungiDB:SCHCODRAFT_02509801; -.
DR eggNOG; KOG0082; Eukaryota.
DR HOGENOM; CLU_014184_1_1_1; -.
DR InParanoid; D8QB49; -.
DR OrthoDB; 5652000at2759; -.
DR Proteomes; UP000007431; Unassembled WGS sequence.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF302; GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-8 SUBUNIT-RELATED; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007431};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 435 AA; 49217 MW; BA4D3724A1F61526 CRC64;
MSISDTVSSR TSRASRKEKR SLEVQASQAS RAIDALIEHE SERRKRARHA LSDIPVLVVG
PSGAGKSTIC KQFSNFYAPH VLEGERALWR PLVFLNLIAA VRAIIDDVDY AVDTGAAVVN
PEVAEVRHRL LPLISMEDSL VNEFNHDTGV GRRTRPCMRL SSLQDGVPRL PGPAPVRELV
ARTICESAHT IRELWRNLYV QHLVRERKML MNSFFNALPR IVDIPYVPTI EDIVHARADS
YGMIEYRIPT ELRGQRRTWM LQDVSGVGGR KPVWANFFDA DGLSKASKTI VFVMSIAAFD
EYILEEPFTN CIEHALKMFA EICSNRLLAG AHFIVMLNKC DVVKQKLQRG VRVREFLRGF
GKRPNTYDEY ADFIRAHVER VYERRPGADR MPGDGKRLTV YFTTLVNIKE TQNILTGLGE
VIQSQRVQLP SECSA
//
