ID D8S8L5_SELML Unreviewed; 1896 AA.
AC D8S8L5;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=1,3-beta-glucan synthase {ECO:0000256|ARBA:ARBA00012589};
DE EC=2.4.1.34 {ECO:0000256|ARBA:ARBA00012589};
DE AltName: Full=1,3-beta-glucan synthase {ECO:0000256|ARBA:ARBA00032165};
GN Name=Gsl2 {ECO:0000313|EMBL:EFJ19064.1};
GN ORFNames=SELMODRAFT_177798 {ECO:0000313|EMBL:EFJ19064.1};
OS Selaginella moellendorffii (Spikemoss).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Lycopodiopsida; Selaginellales; Selaginellaceae; Selaginella.
OX NCBI_TaxID=88036 {ECO:0000313|Proteomes:UP000001514};
RN [1] {ECO:0000313|EMBL:EFJ19064.1, ECO:0000313|Proteomes:UP000001514}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21551031; DOI=10.1126/science.1203810;
RA Banks J.A., Nishiyama T., Hasebe M., Bowman J.L., Gribskov M.,
RA dePamphilis C., Albert V.A., Aono N., Aoyama T., Ambrose B.A., Ashton N.W.,
RA Axtell M.J., Barker E., Barker M.S., Bennetzen J.L., Bonawitz N.D.,
RA Chapple C., Cheng C., Correa L.G., Dacre M., DeBarry J., Dreyer I.,
RA Elias M., Engstrom E.M., Estelle M., Feng L., Finet C., Floyd S.K.,
RA Frommer W.B., Fujita T., Gramzow L., Gutensohn M., Harholt J., Hattori M.,
RA Heyl A., Hirai T., Hiwatashi Y., Ishikawa M., Iwata M., Karol K.G.,
RA Koehler B., Kolukisaoglu U., Kubo M., Kurata T., Lalonde S., Li K., Li Y.,
RA Litt A., Lyons E., Manning G., Maruyama T., Michael T.P., Mikami K.,
RA Miyazaki S., Morinaga S., Murata T., Mueller-Roeber B., Nelson D.R.,
RA Obara M., Oguri Y., Olmstead R.G., Onodera N., Petersen B.L., Pils B.,
RA Prigge M., Rensing S.A., Riano-Pachon D.M., Roberts A.W., Sato Y.,
RA Scheller H.V., Schulz B., Schulz C., Shakirov E.V., Shibagaki N.,
RA Shinohara N., Shippen D.E., Soerensen I., Sotooka R., Sugimoto N.,
RA Sugita M., Sumikawa N., Tanurdzic M., Theissen G., Ulvskov P., Wakazuki S.,
RA Weng J.K., Willats W.W., Wipf D., Wolf P.G., Yang L., Zimmer A.D., Zhu Q.,
RA Mitros T., Hellsten U., Loque D., Otillar R., Salamov A., Schmutz J.,
RA Shapiro H., Lindquist E., Lucas S., Rokhsar D., Grigoriev I.V.;
RT "The Selaginella genome identifies genetic changes associated with the
RT evolution of vascular plants.";
RL Science 332:960-963(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->3)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->3)-
CC beta-D-glucosyl](n+1) + H(+) + UDP; Xref=Rhea:RHEA:21476, Rhea:RHEA-
CC COMP:11146, Rhea:RHEA-COMP:14303, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:37671, ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.34;
CC Evidence={ECO:0000256|ARBA:ARBA00000192};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 48 family.
CC {ECO:0000256|ARBA:ARBA00009040}.
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DR EMBL; GL377607; EFJ19064.1; -; Genomic_DNA.
DR RefSeq; XP_002979662.1; XM_002979616.1.
DR STRING; 88036.D8S8L5; -.
DR EnsemblPlants; EFJ19064; EFJ19064; SELMODRAFT_177798.
DR Gramene; EFJ19064; EFJ19064; SELMODRAFT_177798.
DR KEGG; smo:SELMODRAFT_177798; -.
DR eggNOG; KOG0916; Eukaryota.
DR HOGENOM; CLU_000742_1_1_1; -.
DR InParanoid; D8S8L5; -.
DR Proteomes; UP000001514; Unassembled WGS sequence.
DR GO; GO:0000148; C:1,3-beta-D-glucan synthase complex; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0003843; F:1,3-beta-D-glucan synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0046527; F:glucosyltransferase activity; IBA:GO_Central.
DR GO; GO:0006075; P:(1->3)-beta-D-glucan biosynthetic process; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.270; Vacuolar protein sorting-associated protein vta1; 1.
DR InterPro; IPR026899; FKS1-like_dom1.
DR InterPro; IPR003440; Glyco_trans_48.
DR InterPro; IPR039431; Vta1/CALS_N.
DR InterPro; IPR023175; Vta1/CALS_N_sf.
DR PANTHER; PTHR12741:SF29; 1,3-BETA-GLUCAN SYNTHASE COMPONENT FKS1-RELATED; 1.
DR PANTHER; PTHR12741; LYST-INTERACTING PROTEIN LIP5 DOPAMINE RESPONSIVE PROTEIN DRG-1; 1.
DR Pfam; PF14288; FKS1_dom1; 1.
DR Pfam; PF02364; Glucan_synthase; 2.
DR Pfam; PF04652; Vta1; 1.
DR SMART; SM01205; FKS1_dom1; 1.
PE 3: Inferred from homology;
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001514};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 454..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 491..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 525..547
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 567..590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 629..650
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 703..722
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1465..1488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1508..1530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1542..1562
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1629..1648
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1737..1757
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1777..1795
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1801..1821
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1842..1862
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 299..416
FT /note="1,3-beta-glucan synthase component FKS1-like"
FT /evidence="ECO:0000259|SMART:SM01205"
SQ SEQUENCE 1896 AA; 218843 MW; 5973FF573D89B3CF CRC64;
MTTRLPRTFT TGTFPTEFDS EVVPSSLGPI AAILRVANEV EQDSQRVAYL CRFYAFERAH
YDDPSSSGRG VRQFKTALLQ RLEKDEEPSR LARRERSDAR EMQRFYQNYY DKYVKALEAD
HQDRASLAKA YQTAGILFDV LTSVTRQDGA EVDSEMQAMN TDVTKKKKDI KHYNILPLDA
AGASQAIMKL EEVRAAHDAI ANVRGLPKRK EAPSDILEWL QVMFGFQKDN VANQREHLIL
LLANVHVSLD PEPSPLYKLD QRATEIVMKR MFKNYRTWCK FLGRSDKLEL PEIQLEVQQR
MILYMALYLL IWGEAANVRF MPECLCYIFH HMASELSGML SGRVSYVTGE NIKPAYGSED
EAFLKKVVTP IYNVIFKKES NRNESGGKPH SSWRNYDDLN EYFWSKTCFR LGWPMRKDDE
FFVGAAEEAH SRSSKTNFVE ARSFWHLFRT FDRMWTFFIL WLQAMIIIAW NGSGSLGALF
EGSVFKKVLS VFITAAVLRF FQALLDIIFS FKALHSLGYV GSIRLVLKVL VSAFWIVILS
TSYVHSWEHP TGLTRTIKNL LGHNGGPSVY LVAVILYLVP NAIAAIFFLL PCVRRVAEES
DAIPVRILLW WSQPPCYIGR GMHEEPLHLF SYTFFWIVLI TCKLLFSYYV EIKPLVEPTK
FILDFTNVRF AWHEFFPHAR GNIGVLIALW TPVILVYFMD IQIWYSIMST IWGGVVGAFM
RLGEIRTLSM LRSRFRALPT TFNWNLIPLE SSVKRKYQIL RKFKAHNKLE EARFAHLWNA
VIESLREEDF LDDKEKELML LPYSADPYPS NNIIQWPPFL LASMAPMAIE MAKEYAEVQG
ENVEDARLWN KIKENEYMRC AVEECYEFLK NILLRVVTGD TEKRLIHDLL KELEDRKAEG
KLLENFRMND LPLLAGHFVR FLEFLDKPDP SDTARDKVVL LLQDMLEVFM HDMMKFESSH
GLNMKPTDNQ SVMGGKGKIQ FFAGKDSILY PLPEDHAWSE QIKRVLLLLT ETESAMDVPK
NLDARRRITF FTNSLFMKMP PAPRVRKMIP FSVLTPFYEE EVLYSKNVIE EPNEDGVSIL
FYLQNVYPDE WNKFLERVNC STEEEVEEAA LRDWTSYRGQ TLSRTVRGMM YYRTALELQA
FLDLAPDEDV YTGFKEVSKR RKEEKGQDSF WAKLDAIVDM KFTFVATCQK FGQQKHSKDL
KEASKAQDIQ KLMTKYPSLR VAYVLEEEPS KGKPQKSYYS VLSKAVDGRD EEIYKIRLPG
PVNIGEGKPE NQNHAIIFTR GLGLQTIDMN QENYLEEAFK VRNLLEEFKS RHGARFPTIL
GVREHIFTGS VSSLAWFMSN QETSFVTIGQ RVLATPLKVR FHYGHPDVFD RIFHITRGGV
SKASKGINLS EDIFAGFNST LRRGLVTHHE YIQVGKGRDV GLNQISIFEA KVANGNGEQT
LSRDVYRLGH RFDFFRMLSF YITTVGYYFS TMIVILTVYV FLYGRLYLAL SGLERSFVRA
AQQNTDSALQ SALASQSLIQ LGLLMALPMV MEIGLERGFR MALSDLIVMQ LQLASVFFTF
TLGSKVHYYG RTIFHGGAKY RATGRGFVVR HEKFPDNYRL YSRSHFVKGF ELMILLIIYD
VYGSQTRNAV SYVLITFSMW FLVGTWLFSP FLFNPSGFEW QKIVEDWNDW NKWISSKGRI
GVPANKSWES WWEEEQDHLQ NTGFRGRVFE VILALRFVLY QYGIVYQLNI MRGNKSLSMY
GLSWVVICVV LFTLKAVSLG RKKFKANFQL VFRMLKGVIF VAVLSVIAVL FRFAHLTVGD
LFASILAFVP TGWGLLQIFQ ACRPVIVTYG MWDSVQALAR TYEYVMGLLL FAPVAILAWF
PFVSEFQTRL LFNQAFSRGL QISRILAGKR KKVADD
//
