ID D8U096_VOLCA Unreviewed; 1660 AA.
AC D8U096;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000259|PROSITE:PS50042};
GN ORFNames=VOLCADRAFT_92690 {ECO:0000313|EMBL:EFJ46902.1};
OS Volvox carteri f. nagariensis.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Chlamydomonadales; Volvocaceae; Volvox.
OX NCBI_TaxID=3068 {ECO:0000313|Proteomes:UP000001058};
RN [1] {ECO:0000313|EMBL:EFJ46902.1, ECO:0000313|Proteomes:UP000001058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=f. Nagariensis / Eve {ECO:0000313|Proteomes:UP000001058};
RX PubMed=20616280; DOI=10.1126/science.1188800;
RA Prochnik S.E., Umen J., Nedelcu A.M., Hallmann A., Miller S.M., Nishii I.,
RA Ferris P., Kuo A., Mitros T., Fritz-Laylin L.K., Hellsten U., Chapman J.,
RA Simakov O., Rensing S.A., Terry A., Pangilinan J., Kapitonov V., Jurka J.,
RA Salamov A., Shapiro H., Schmutz J., Grimwood J., Lindquist E., Lucas S.,
RA Grigoriev I.V., Schmitt R., Kirk D., Rokhsar D.S.;
RT "Genomic analysis of organismal complexity in the multicellular green alga
RT Volvox carteri.";
RL Science 329:223-226(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the potassium channel family. Plant (TC 1.A.1.4)
CC subfamily. {ECO:0000256|ARBA:ARBA00007929}.
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DR EMBL; GL378348; EFJ46902.1; -; Genomic_DNA.
DR RefSeq; XP_002952111.1; XM_002952065.1.
DR SMR; D8U096; -.
DR GeneID; 9617254; -.
DR KEGG; vcn:VOLCADRAFT_92690; -.
DR eggNOG; KOG0498; Eukaryota.
DR InParanoid; D8U096; -.
DR OrthoDB; 316559at2759; -.
DR Proteomes; UP000001058; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR InterPro; IPR045319; KAT/AKT.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45743; POTASSIUM CHANNEL AKT1; 1.
DR PANTHER; PTHR45743:SF2; POTASSIUM CHANNEL AKT1; 1.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR01463; EAGCHANLFMLY.
DR SMART; SM00248; ANK; 6.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001058};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 265..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 464..483
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 495..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 598..683
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REPEAT 888..920
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 987..1020
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1206..1230
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 130..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1314..1340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1359..1399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1589..1660
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1609..1624
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1660 AA; 175272 MW; 6BBC52D3023F5F74 CRC64;
MSSNLRKEDD RDCGAGHHEC LRGRWLNTVN ELSTALCVTA AKDLELKRLV LQTASQQVCL
LHIHSFAPSQ MDSVAPGALH VVKSSAELPR GSVESGIPAG AHSQVRRFQK RTARISELLE
ESAIQDKLTA LSSDDVDQQH RNGSGGGVTS SMAGGRNCSQ DGSEAGSVSA RIGGASGRHN
WRKLNKAVVA TKVLASRPNA LAQGRQPARQ ALAQQKQVAS SKDIATTSNF FLGARETPWL
RIKESLSNAL TFLAMRVVIL PETSWYQVWW FYYAVAIAIV SCWVEPFQMA FQHPGMPTAV
WMTALEYVII VTFLLDFLFK FVVAYFDPET GVLVTAQPKM AIAYCRSVKF FLDILGCFPY
DMLVSAIARR CGASNKIEDS VDWLKLMALS RAYRVFDLFH VLDYRMMLSQ GTLMLLRNYT
YVFFTAHWAA CIFFHMAHEE RNYRHGNDDS WVGRNGPAFM GRPLYEQYIL SLYFTVTIFT
SMGDGRLYPF TIVELSVMIV YLLFNLFLGA YIIGTVTIMM VRADEHSKSF RDSMTHLVEY
SRENELPERL YKAMREHLEV HFDSAQTADD NVLSIYPTTI RRLVLRHLYL QPVRSCYLFK
GCKQRFLDAL LTAARVELFL PGVEIMTEGD NVVELLIVML GECLVSRGGQ RVGGVYGMST
LGASAVGSDS NISFLTGSSR NATSDGGGSF VGSAVGSKAE VSVNVRDGSL NCSQMHAGSA
TPLLSPGGVL LSPLPPGLPP KIPNLTSTLK KGPSDALAEI AFFTDGASYE TVVGRTPVRV
LSLPKAAWEL LVQQFPQQLH VALSLVSGKE FVDTTDPVLL AQTRDALTHH QMEMITRLDD
IRTVAATHTR KCDEMRTFEF LNTAAQGDVE SLRTMLAQGI SPNTADYDGR TGLMLAAAKG
HNETVQLLLD AGADKDKTDA FGISALAEAV KNEHDSTIEL MLKYGATLGA GGLTVAAEMC
TAVYEGDLVK LRRLLRSGAP PDACDYDKRS ALHIAGAEGN LAAVKLLVEE GGADPNFQDR
WGNTALDEAR RVGAAPVLAY LEGRQKRDAG VTAEKKRQQA AHEFMSWCGL GQVSELRNAG
GYSFGDEAGC VFAGLLLAAS KGHTEVVEVL LEGMPSEVLW NHAHVAMMEA ARMAHPDTVT
AFRRAGVALC DPGGTTTATS ASCPSSGPMM MRSLIADLRA AAQQGSGTVL EALLAAGVPG
TRQPGDSTSP LHVAVEYGHL GVARRLVEHG GAAADLLSLD GLGRTPLQVA EHLSSMRPHD
LHAKAVHEYL VWAAPLAAAG TGPAALAAAA VEQWGPIGHP AIDPHAPEVA ALLGTPQTPS
ISGGAGGGGA GVKSSLSPGV DCRTDERLTL PSALRASCIS RGSNTPQLGS GGGGGGGGAS
EAPQGPHRQP GTDPPPLHTV VEECSGAVSI STETGNGNLD DNSVAAGADG GAAAAAGGLV
AIPSPELPTS FSVPDVVGMW DSSLPGTPGD STRGGTGAGT LLAALAARRG PAEAAQLYNA
TVQHSAVLLN EPPSQLPDAA GGIATGLPSP APAASWLRRR SSTFSPVVED EIEQYMAALA
DGNDTAPAAA PAAPAAAPAG LQVPEAREAL ASPGGAAQRH LPSRLGGSRL GSQGISSAPS
GRAGGSGVSS PAIPGDGTGL VREGSGAAGS PLSPRGSLRS
//
