ID D9HND8_PLAFA Unreviewed; 727 AA.
AC D9HND8;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Putative erythrocyte membrane protein {ECO:0000313|EMBL:ADI99360.1};
DE Flags: Fragment;
GN ORFNames=PF10_0355 {ECO:0000313|EMBL:ADI99360.1};
OS Plasmodium falciparum (malaria parasite P. falciparum).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5833 {ECO:0000313|EMBL:ADI99360.1};
RN [1] {ECO:0000313|EMBL:ADI99360.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=336 {ECO:0000313|EMBL:ADI99360.1};
RX PubMed=20457586; DOI=10.1093/molbev/msq119;
RA Ochola L.I., Tetteh K.K., Stewart L.B., Riitho V., Marsh K., Conway D.J.;
RT "Allele frequency-based and polymorphism-versus-divergence indices of
RT balancing selection in a new filtered set of polymorphic genes in
RT Plasmodium falciparum.";
RL Mol. Biol. Evol. 0:0-0(2010).
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DR EMBL; HM000380; ADI99360.1; -; Genomic_DNA.
DR AlphaFoldDB; D9HND8; -.
DR VEuPathDB; PlasmoDB:PfCD01_100041200; -.
DR VEuPathDB; PlasmoDB:PfGB4_100040900; -.
DR VEuPathDB; PlasmoDB:PfHB3_100040400; -.
DR VEuPathDB; PlasmoDB:PfKH01_100040500; -.
DR VEuPathDB; PlasmoDB:PfNF166_100040700; -.
DR VEuPathDB; PlasmoDB:PfSD01_100040600; -.
DR VEuPathDB; PlasmoDB:PfTG01_100041200; -.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro.
DR Gene3D; 1.20.58.830; -; 1.
DR Gene3D; 1.20.1310.20; Duffy-antigen binding domain; 1.
DR InterPro; IPR042202; Duffy-ag-bd_sf.
DR InterPro; IPR008602; Duffy-antigen-binding.
DR InterPro; IPR010784; Merozoite_SPAM.
DR Pfam; PF05424; Duffy_binding; 1.
DR Pfam; PF07133; Merozoite_SPAM; 1.
DR SUPFAM; SSF140924; Duffy binding domain-like; 1.
PE 4: Predicted;
FT DOMAIN 178..324
FT /note="Duffy-antigen binding"
FT /evidence="ECO:0000259|Pfam:PF05424"
FT REGION 445..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..504
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..533
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..649
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 650..691
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADI99360.1"
FT NON_TER 727
FT /evidence="ECO:0000313|EMBL:ADI99360.1"
SQ SEQUENCE 727 AA; 83073 MW; EB6A40512BB7026C CRC64;
STCFVVNEGN PNLRNNIIND DDLKGKAYNN TIDANNQNIE YNKNLEHNVN SSHISKFSDI
MDQEDKGDNE NSHDIKFEEK KNINKSLDAE SNYGINEISI TGNDSNSDNS NQNIFPDGSE
LAGGIAPSIY SINLGPNKCP VEKICKDFGP LPQCRKDVHE RNNWLSSNVK NFSSDYKGVL
VPPRRQFLCL RITLQNFRAK KKNEGDFEKF IYSYASSEAK KLRTIHNNIS EKALQAIKYS
FADIGNIIKG DDLLDTPTSN NTKTYLEEVL KLHNKNNETK DAKKWWTENR YHVWEAMMCG
YQNEKKDNEC TVYGNIDDIP QFLRWFREWG TYVCEESENN MKTLKAVCFP KQLRTETNSA
MTVTQKGTCS STLKNYEEWY NKRKNEWTEQ SIKYNKDKTK YKDIENLSPS NYLIKKCPEC
KCTEKNLHDV FEHTFDGKAL LKKLEEEESP ASDSVRTSTE SGPITVPDSS LNQTTQQENQ
PGVEKPLTTV VMNEHQGQTD PNTDDNSGET EHNKSNVGSI QEVNQGSVSE ESHSKTIDPS
KIDDRLELSS GSSSLEQHSK EDVKKGSALE LVPLSLSDIE QIANESEDVL EEIEEEINTD
GEIEYITEEE IKEDIEEETE EDIEEETEEE TEEETEEETE EEADEETVKE IEDKPEQEIK
NKSLEEKQID KNTDTSEKKG FNNSEKDEKA RNLISKNYKN YNELDKNVHT LVNSIISLLE
EGNGSDS
//
