ID D9IU89_9SAUR Unreviewed; 196 AA.
AC D9IU89;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Nerve growth factor beta {ECO:0000313|EMBL:ADJ80264.1};
DE Flags: Fragment;
GN Name=NGFB {ECO:0000313|EMBL:ADJ80264.1};
OS Hemidactylus fasciatus (banded leaf-toed gecko).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Gekkota; Gekkonidae; Gekkoninae;
OC Hemidactylus.
OX NCBI_TaxID=401547 {ECO:0000313|EMBL:ADJ80264.1};
RN [1] {ECO:0000313|EMBL:ADJ80264.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20519219; DOI=10.1098/rspb.2010.0662;
RA Leache A.D., Fujita M.K.;
RT "Bayesian species delimitation in West African forest geckos (Hemidactylus
RT fasciatus).";
RL Proc. R. Soc. B 277:3071-3077(2010).
RN [2] {ECO:0000313|EMBL:ADJ80264.1}
RP NUCLEOTIDE SEQUENCE.
RA Leache A., Fujita M.K.;
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the NGF-beta family.
CC {ECO:0000256|ARBA:ARBA00010783}.
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DR EMBL; HM180155; ADJ80264.1; -; Genomic_DNA.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0008191; F:metalloendopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR020408; Nerve_growth_factor-like.
DR InterPro; IPR002072; Nerve_growth_factor-rel.
DR InterPro; IPR020425; Nerve_growth_factor_bsu.
DR InterPro; IPR019846; Nerve_growth_factor_CS.
DR PANTHER; PTHR11589:SF10; BETA-NERVE GROWTH FACTOR; 1.
DR PANTHER; PTHR11589; NERVE GROWTH FACTOR NGF -RELATED; 1.
DR Pfam; PF00243; NGF; 1.
DR PIRSF; PIRSF001789; NGF; 1.
DR PRINTS; PR00268; NGF.
DR PRINTS; PR01913; NGFBETA.
DR SMART; SM00140; NGF; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00248; NGF_1; 1.
DR PROSITE; PS50270; NGF_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Metalloenzyme inhibitor {ECO:0000256|ARBA:ARBA00023215};
KW Metalloprotease inhibitor {ECO:0000256|ARBA:ARBA00022608};
KW Protease inhibitor {ECO:0000256|ARBA:ARBA00022690};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 117..196
FT /note="Nerve growth factor-related"
FT /evidence="ECO:0000259|SMART:SM00140"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADJ80264.1"
FT NON_TER 196
FT /evidence="ECO:0000313|EMBL:ADJ80264.1"
SQ SEQUENCE 196 AA; 22100 MW; BFAB96EF73EF06AD CRC64;
GIWAAPKFED NAPLGSPATS DISERSQNKA YHVVKMVQHR DHNQPGTSKV EDRKVGQPAN
IKVDPKLFQK RRFQSPRVLF STQPPPLSRD GQGLEFLDST DSLNRNIRAK RSTHPVHNRG
EYSVCDSISV WVANKTTATD IKGKQVTVMV DVNINNSAYK QYFFETRCXD PKPVSSGCRG
IDARHWNSYC TTTHTF
//
