ID D9PU46_METTM Unreviewed; 620 AA.
AC D9PU46;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Predicted NADH dehydrogenase {ECO:0000313|EMBL:ADL57744.1};
GN OrderedLocusNames=MTBMA_c01350 {ECO:0000313|EMBL:ADL57744.1};
OS Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM
OS 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium
OS thermoautotrophicum).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX NCBI_TaxID=79929 {ECO:0000313|EMBL:ADL57744.1, ECO:0000313|Proteomes:UP000000345};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Marburg;
RA Kaster A., Seedorf H., Goenrich M., Wiezer A., Liesegang H., Thauer R.,
RA Gottschalk G.;
RT "The genome sequence of Methanothermobacter marburgensis.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADL57744.1, ECO:0000313|Proteomes:UP000000345}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 /
RC Marburg {ECO:0000313|Proteomes:UP000000345};
RX PubMed=20802048; DOI=10.1128/JB.00844-10;
RA Liesegang H., Kaster A.K., Wiezer A., Goenrich M., Wollherr A., Seedorf H.,
RA Gottschalk G., Thauer R.K.;
RT "Complete genome sequence of Methanothermobacter marburgensis, a
RT methanoarchaeon model organism.";
RL J. Bacteriol. 192:5850-5851(2010).
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
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DR EMBL; CP001710; ADL57744.1; -; Genomic_DNA.
DR AlphaFoldDB; D9PU46; -.
DR STRING; 79929.MTBMA_c01350; -.
DR PaxDb; 79929-MTBMA_c01350; -.
DR KEGG; mmg:MTBMA_c01350; -.
DR HOGENOM; CLU_014881_3_2_2; -.
DR OrthoDB; 297477at2157; -.
DR Proteomes; UP000000345; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR CDD; cd02980; TRX_Fd_family; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR001949; NADH-UbQ_OxRdtase_51kDa_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF13187; Fer4_9; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF10531; SLBB; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS00645; COMPLEX1_51K_2; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 553..582
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 583..612
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 620 AA; 67272 MW; 486C48455E96C8AA CRC64;
MFEDTAGRAL DEYMSLFRDE PVIFLGSATC GRSAGAHEIE RVLLERASEL SVECSIVHTG
CMGLCYAEPM VTVFNGDTRG AIYGPVNRRL AKRIIQELAD GEEFSAIGSL NVAFNGDSFE
PSYSIDFMEK QSRRILRRGG LIDPENINHY LATGGYRGLL RALEMKPEDI IEEVKDSGLR
GRGGAGFPTW LKWSLCRQEE SDVKYLVCNA DEGDPGAFMN RSLIEGDPHS LLEGILIASY
AVGAEEAYIY CRAEYPLALE RLRTAISDLR DLGLLGEDIL DSGFSLDIRI KEGAGAFVCG
EETALIASIE GKRGMPRTRP PFPTTSGLWG KPTVINNVET LAAVSMIMQH GPEYFNTPGT
EGSPGTKTFS LVGDVRRTGL IEVPLGTSLR EVIHDIGGGV RDGELKAVQI GGPSGGCLPA
ELVDTGIDYD SLTSAGAIMG SGGLVVLSDH TCMVELARYF LEFTQRESCG KCVPCRVGTR
QMLMILNDIV EGSGREEDLE ILRDIAETVR AASLCGLGQT SPNPVLTTLR YFEREYRDHI
NGKCTAASCS QLMHYLIEAE KCDGCMACLK TCPADAIEGS KDEVHVIDQE SCLKCGSCLD
TCKRDAVLRV PGPYSPANQD
//
