ID D9Q1Z0_ACIS3 Unreviewed; 695 AA.
AC D9Q1Z0;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN OrderedLocusNames=ASAC_0922 {ECO:0000313|EMBL:ADL19328.1};
OS Acidilobus saccharovorans (strain DSM 16705 / JCM 18335 / VKM B-2471 /
OS 345-15).
OC Archaea; Thermoproteota; Thermoprotei; Acidilobales; Acidilobaceae;
OC Acidilobus.
OX NCBI_TaxID=666510 {ECO:0000313|EMBL:ADL19328.1, ECO:0000313|Proteomes:UP000000346};
RN [1] {ECO:0000313|EMBL:ADL19328.1, ECO:0000313|Proteomes:UP000000346}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16705 / JCM 18335 / VKM B-2471 / 345-15
RC {ECO:0000313|Proteomes:UP000000346};
RX PubMed=20581186; DOI=10.1128/AEM.00599-10;
RA Mardanov A.V., Svetlitchnyi V.A., Beletsky A.V., Prokofeva M.I.,
RA Bonch-Osmolovskaya E.A., Ravin N.V., Skryabin K.G.;
RT "The genome sequence of the crenarchaeon Acidilobus saccharovorans supports
RT a new order, Acidilobales, and suggests an important ecological role in
RT terrestrial acidic hot springs.";
RL Appl. Environ. Microbiol. 76:5652-5657(2010).
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|ARBA:ARBA00008010,
CC ECO:0000256|RuleBase:RU004070}.
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DR EMBL; CP001742; ADL19328.1; -; Genomic_DNA.
DR RefSeq; WP_013266840.1; NC_014374.1.
DR AlphaFoldDB; D9Q1Z0; -.
DR STRING; 666510.ASAC_0922; -.
DR GeneID; 9499162; -.
DR KEGG; asc:ASAC_0922; -.
DR eggNOG; arCOG00439; Archaea.
DR HOGENOM; CLU_000995_7_2_2; -.
DR InParanoid; D9Q1Z0; -.
DR Proteomes; UP000000346; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 3.30.1640.10; mini-chromosome maintenance (MCM) complex, chain A, domain 1; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR027925; MCM_N.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; NF040949; minchrom_main_MCM; 1.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF43; DNA REPLICATION LICENSING FACTOR MCM6; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF14551; MCM_N; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004070};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ADL19328.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004070};
KW Reference proteome {ECO:0000313|Proteomes:UP000000346}.
FT DOMAIN 292..498
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
SQ SEQUENCE 695 AA; 78217 MW; CDB0427D2C07A81F CRC64;
MSAAEQEQLS IGEKFKDFIR NFRSVEGLKY MDRLHRMINL DLGSLLVDFQ DLYRYNTDLA
NMLIDEPQKV LKEFDEALLE LVTGEDAEFA KRKGKLHVRV QGLYETTKIR DIKTQYMNKL
IQVEGIITRM RPVRSKMIKA VYRHEKEGCN AEFQWPYEED EYLEDKIDRP LQCPVCGEAG
GRFVLLRDKS VYVDWQEITL QERPEDVPGG QMPRSVTVEL TEDLVDMARP GDLVTVVGIV
RPSPAAGNDK APYFELKIEA NSLRVSEKVL EEVAITRDDE EKILELSKDP WIREKIIASV
APTIYGHWDL KEAIALQLFG GVPKVAPDGT RIRGDIHVLF VGDPGVAKSQ LLQSAARIAP
RSVYTSGKGS TAAGLTAAVL KDPKTSEYFL EAGAMVLADG GLAVIDEFDK MRPEDRASIH
EAMEQQSVSI SKAGIVARLN ARAAVLAAGN PKYGLYDPQR SFIDNVNLPP TVLSRFDLIF
VVKDVMAMEH DRRLARYILD VHSDYSKYVP EIDPQLLKKY IIYAKRYSRP KLTEEAKSII
ESFFVTMRSS ASKYGNEGQT PVPVTARQLE ALVRLSEAHA RMALKDRVDA EDAEEAVRLM
LSFLGSVGLD VESGFIDYSM IATGASFHTR KLMTVIVDTI KRLREDGRPC VKLDDIIKEV
TSQTKAAPDK VEETIRAMNR QGQIAEIRSN CYKEV
//
