ID D9S090_THEOJ Unreviewed; 548 AA.
AC D9S090;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Cobalamin B12-binding domain protein {ECO:0000313|EMBL:ADL07018.1};
GN OrderedLocusNames=Toce_0232 {ECO:0000313|EMBL:ADL07018.1};
OS Thermosediminibacter oceani (strain ATCC BAA-1034 / DSM 16646 /
OS JW/IW-1228P).
OC Bacteria; Bacillota; Clostridia; Thermosediminibacterales;
OC Thermosediminibacteraceae; Thermosediminibacter.
OX NCBI_TaxID=555079 {ECO:0000313|EMBL:ADL07018.1, ECO:0000313|Proteomes:UP000000272};
RN [1] {ECO:0000313|EMBL:ADL07018.1, ECO:0000313|Proteomes:UP000000272}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1034 / DSM 16646 / JW/IW-1228P
RC {ECO:0000313|Proteomes:UP000000272};
RX PubMed=21304740;
RA Pitluck S., Yasawong M., Munk C., Nolan M., Lapidus A., Lucas S.,
RA Glavina Del Rio T., Tice H., Cheng J.F., Bruce D., Detter C., Tapia R.,
RA Han C., Goodwin L., Liolios K., Ivanova N., Mavromatis K., Mikhailova N.,
RA Pati A., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J.,
RA Jeffries C.D., Rohde M., Spring S., Sikorski J., Goker M., Woyke T.,
RA Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C.,
RA Klenk H.P.;
RT "Complete genome sequence of Thermosediminibacter oceani type strain
RT (JW/IW-1228P).";
RL Stand. Genomic Sci. 3:108-116(2010).
CC -!- COFACTOR:
CC Name=adenosylcob(III)alamin; Xref=ChEBI:CHEBI:18408;
CC Evidence={ECO:0000256|ARBA:ARBA00001922};
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DR EMBL; CP002131; ADL07018.1; -; Genomic_DNA.
DR RefSeq; WP_013275069.1; NC_014377.1.
DR AlphaFoldDB; D9S090; -.
DR STRING; 555079.Toce_0232; -.
DR KEGG; toc:Toce_0232; -.
DR eggNOG; COG5012; Bacteria.
DR HOGENOM; CLU_495139_0_0_9; -.
DR OrthoDB; 5756833at2; -.
DR Proteomes; UP000000272; Chromosome.
DR GO; GO:0031419; F:cobalamin binding; IEA:UniProtKB-KW.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd02065; B12-binding_like; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.20.20.240; Methylmalonyl-CoA mutase; 1.
DR InterPro; IPR016176; Cbl-dep_enz_cat.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR Pfam; PF02310; B12-binding; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF51703; Cobalamin (vitamin B12)-dependent enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
PE 4: Predicted;
KW Cobalamin {ECO:0000256|ARBA:ARBA00022628};
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000000272}.
FT DOMAIN 1..131
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 548 AA; 61307 MW; 2A37261FCC84C354 CRC64;
MKRILGATIG SCVHVAGVMN FLSLAEREGY EVEFLGAAVS IDELIAAVKE RMPDYVGVGY
RLTPEPLREV LKELKEKIKA HGLDSGIKWI FGGTEPTAKV AEESGIFTKI FNGLEDIDEV
IGFLKGYRRS TEETYPEDLI SRIESKYPYP ILRHHLGLPS LEATIEAIEK VAEAKVLDVI
SIAPDQNAQE YFFEQDKMDR RLDGAGGVPV RSREDFLALY RASRRGNYPL LRCYSGTSHL
IEFAELLNET IKNAWCAVPL CWYNVLDKRG PRLLRDSIRE NQQVMKWHGE RGIPVEVNES
HHWSLRDAHD TVGVATAFLA AYNAKKMGVK HYIAQYMFNV PPSLSPRMDL AKMLAKIELI
ESLQDENFRV YRQARAGLAS FPGDLAQAKG QLASSAYLAM AIKPHIYHVV GFCEAHHAAT
AEDIIESCKI VRGVIRNAFL GLPDLVNDPV VQERKKQLVD EAMITLEAIK RLNPGAEDPW
TDPDTIARAV ELGILDAPHL KGNPAACGKL VTRLVDGALY AYDPEENRVL TETERIEKIF
KRAEITVS
//
