ID   D9SUG4_CLOC7            Unreviewed;       651 AA.
AC   D9SUG4;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   RecName: Full=Nephrocystin-3 {ECO:0000256|ARBA:ARBA00040387};
GN   OrderedLocusNames=Clocel_3233 {ECO:0000313|EMBL:ADL52919.1};
OS   Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=573061 {ECO:0000313|EMBL:ADL52919.1, ECO:0000313|Proteomes:UP000002730};
RN   [1] {ECO:0000313|EMBL:ADL52919.1, ECO:0000313|Proteomes:UP000002730}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35296 / DSM 3052 / OCM 3 / 743B
RC   {ECO:0000313|Proteomes:UP000002730};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Chang Y.-J., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N.,
RA   Hemme C.L., Woyke T.;
RT   "Complete sequence of Clostridium cellulovorans 743B.";
RL   Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002160; ADL52919.1; -; Genomic_DNA.
DR   RefSeq; WP_010073304.1; NC_014393.1.
DR   AlphaFoldDB; D9SUG4; -.
DR   STRING; 573061.Clocel_3233; -.
DR   KEGG; ccb:Clocel_3233; -.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG3903; Bacteria.
DR   HOGENOM; CLU_000288_125_8_9; -.
DR   OrthoDB; 9815923at2; -.
DR   Proteomes; UP000002730; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005871; C:kinesin complex; IEA:InterPro.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR002151; Kinesin_light.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR45641:SF1; NEPHROCYSTIN-3; 1.
DR   PANTHER; PTHR45641; TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870); 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF13374; TPR_10; 1.
DR   Pfam; PF13424; TPR_12; 3.
DR   PRINTS; PR00381; KINESINLIGHT.
DR   SMART; SM00028; TPR; 6.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50005; TPR; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002730};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW   ProRule:PRU00339}; Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT   DOMAIN          12..175
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
FT   REPEAT          452..485
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          494..527
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          536..569
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   651 AA;  74993 MW;  FD8AF6763FBE99D3 CRC64;
     MPVNGVKLIG REAELKEVDE QLSSGDMVIL VSAIGGVGKT ELCKSYFNKY KTKYNSAIWI
     DYKGSLKESF ANQCKLDSFI EDDNIDQRFE KVIKYYEDEN NSNSLIIIDN VDNEEDQSLL
     QITNLISNNI RILVTSRMVI EGYSTYSLEF LNKDNCKKLF YQYYKRQEDD SNLEKIISLA
     ARHTLIIELL AKTAQNSRIS IKKLYEILLD KGFNLNEVIK EKVSMIKDGN IVSEQLFNQL
     LKIFDLSTIS EEEQYILMNL SILPQVGLQE LVEWIELETM EEINSLEKKG WISINSVDAK
     DIIYVHPLIQ ETIRYQLNPT TDKCVKLIEA IIRALHTRPT DNSLDKKVYT IFGDYILKYI
     DEETERIATL SNNLSSIYID LGNLGKSLEY QHKAVDIREK VLGENHPDLA TAYNNLSSIY
     KILGIPEKSP EYQHKAVEIY EEMLGDEHPF LATSYNNLSL IYQDLGEVEK SLEYQKKAVD
     IREKVLGKKH PDLAISYNNL SMIYRDLGEL EKSLEYQQKA VEIYEEMLGK KHPSLATSYN
     NLSLIYKDFG NMKKSLKYQE KAIEINEKAL GENHLYMAIS YNNLCSIYQG LGELEKSLEF
     QLKAIDIAEK VLPSNHPNLL IFRNNLANIY KKIGQVDESQ SSHLNTEEVF K
//