ID D9UBV5_STRPR Unreviewed; 292 AA.
AC D9UBV5;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=N-methylase {ECO:0000313|EMBL:CBW45752.1};
DE EC=2.1.1.- {ECO:0000313|EMBL:CBW45752.1};
DE SubName: Full=PapM {ECO:0000313|EMBL:ALC18609.1};
DE SubName: Full=Peptide chain release factor N(5)-glutamine methyltransferase {ECO:0000313|EMBL:QMU12424.1};
GN Name=papM {ECO:0000313|EMBL:CBW45752.1};
GN ORFNames=H3L99_01550 {ECO:0000313|EMBL:QMU12424.1}, SPRI_0303
GN {ECO:0000313|EMBL:ALC18609.1}, SPRI_7050
GN {ECO:0000313|EMBL:ALC25356.1};
OS Streptomyces pristinaespiralis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=38300 {ECO:0000313|EMBL:CBW45752.1};
RN [1] {ECO:0000313|EMBL:CBW45752.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Pr11 {ECO:0000313|EMBL:CBW45752.1};
RA Mast Y.J.;
RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBW45752.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Pr11 {ECO:0000313|EMBL:CBW45752.1};
RX PubMed=21342465; DOI=10.1111/j.1751-7915.2010.00213.x;
RA Mast Y., Weber T., Golz M., Ort-Winklbauer R., Gondran A., Wohlleben W.,
RA Schinko E.;
RT "Characterization of the 'pristinamycin supercluster' of Streptomyces
RT pristinaespiralis.";
RL Microb. Biotechnol. 4:192-206(2011).
RN [3] {ECO:0000313|EMBL:ALC18609.1, ECO:0000313|Proteomes:UP000060513}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HCCB 10218 {ECO:0000313|EMBL:ALC18609.1,
RC ECO:0000313|Proteomes:UP000060513};
RA Tian J., Yang J., Li L., Ruan L., Wei W., Zheng G., Wei Z., Yang S., Ge M.,
RA Jiang W., Lu Y.;
RT "Genome sequence of the pristinamycin over-producing bacterium Streptomyces
RT pristinaespiralis HCCB10218.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:QMU12424.1, ECO:0000313|Proteomes:UP000514765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PR11 {ECO:0000313|EMBL:QMU12424.1,
RC ECO:0000313|Proteomes:UP000514765};
RA Handel F., Kulik A., Mast Y.;
RT "Investigation of the effector binding capability of pristinamycin
RT transcriptional regulators.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP011340; ALC18609.1; -; Genomic_DNA.
DR EMBL; CP011340; ALC25356.1; -; Genomic_DNA.
DR EMBL; FR682001; CBW45752.1; -; Genomic_DNA.
DR EMBL; CP059696; QMU12424.1; -; Genomic_DNA.
DR RefSeq; WP_005321573.1; NZ_CP059696.1.
DR STRING; 38300.SPRI_0303; -.
DR KEGG; spri:SPRI_0303; -.
DR KEGG; spri:SPRI_7050; -.
DR PATRIC; fig|38300.4.peg.318; -.
DR OMA; HERCNRI; -.
DR OrthoDB; 9800643at2; -.
DR Proteomes; UP000060513; Chromosome.
DR Proteomes; UP000514765; Chromosome.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR GO; GO:0043412; P:macromolecule modification; IEA:UniProt.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR004556; HemK-like.
DR InterPro; IPR041698; Methyltransf_25.
DR InterPro; IPR040758; PrmC_N.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00536; hemK_fam; 1.
DR PANTHER; PTHR18895; HEMK METHYLTRANSFERASE; 1.
DR PANTHER; PTHR18895:SF74; MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE; 1.
DR Pfam; PF13649; Methyltransf_25; 1.
DR Pfam; PF17827; PrmC_N; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:CBW45752.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:CBW45752.1}.
FT DOMAIN 10..78
FT /note="Release factor glutamine methyltransferase N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF17827"
FT DOMAIN 124..192
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13649"
SQ SEQUENCE 292 AA; 30846 MW; D2E46FA38E70955C CRC64;
MTAAAPTLAQ ALDEATGQLT GAGITADAAR ADTRLLAAHA CQVAPGDLDT CLAGPVPPRF
WHYVRRRLTR EPAERIVGHA YFMGHRFDLA PGVFVPKPET EEITRDAIAR LEALVRRGTP
APLVVDLCAG PGTMAVTLAR HVPAARVLGI ELSQAAARAA RRNARGTGAR IVQGDARDAF
PELSGTVDLV VTNPPYIPIG LRTSAPEVLE HDPPLALWAG EEGLGMIRAM ERTAARLLAP
GGVLLLEHGS YQLASVPALF RATGRWSHAS SRPTCNDGCL TAVRNHTCAP PA
//
