ID   D9WP57_9ACTN            Unreviewed;       915 AA.
AC   D9WP57;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase (GGDEF EAL domains) with GAF sensor {ECO:0000313|EMBL:EFL28030.1};
GN   ORFNames=SSOG_07744 {ECO:0000313|EMBL:EFL28030.1};
OS   Streptomyces himastatinicus ATCC 53653.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group.
OX   NCBI_TaxID=457427 {ECO:0000313|EMBL:EFL28030.1, ECO:0000313|Proteomes:UP000003963};
RN   [1] {ECO:0000313|EMBL:EFL28030.1, ECO:0000313|Proteomes:UP000003963}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53653 {ECO:0000313|EMBL:EFL28030.1,
RC   ECO:0000313|Proteomes:UP000003963};
RG   The Broad Institute Genome Sequencing Platform;
RG   Broad Institute Microbial Sequencing Center;
RA   Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA   Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA   Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA   Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA   Haas B., Nusbaum C., Birren B.;
RT   "Annotation of Streptomyces hygroscopicus strain ATCC 53653.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG657754; EFL28030.1; -; Genomic_DNA.
DR   AlphaFoldDB; D9WP57; -.
DR   STRING; 457427.SSOG_07744; -.
DR   HOGENOM; CLU_000445_43_4_11; -.
DR   Proteomes; UP000003963; Unassembled WGS sequence.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   Gene3D; 3.30.450.40; -; 2.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
PE   4: Predicted;
FT   DOMAIN          365..546
FT                   /note="GAF"
FT                   /evidence="ECO:0000259|SMART:SM00065"
FT   DOMAIN          564..786
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
FT   REGION          314..336
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   915 AA;  98340 MW;  E3D29E7570B9AEF2 CRC64;
     MAGGIGPARS RERFLEGEAV QAGVRGLILN SWQRCRMLGL PLGGFELPYR QVDSEGRLVR
     AAAPVLDRLR ARFRGSPMNI ALADGDGTVL QRRFGDDAWA RTLPPIQQTP GFVFAEQFAG
     TNGIGLALAE RRLIQVYGAE HFSERGLSNG CSAIPVRDPL SGRIEGILCM AFPRSSGHPV
     LDGVLRRAAQ AIERRLLAQS SARERGLLRA YLDAAGATGT GEGGAHTMGV DAFVQGLPRG
     DQMMIKEWAA ELLSHGQRAA IGVTLSDGRR VTLVSRPMTS AAGVEGMVIE AMFPDHSPRP
     SLSLPLHLTI PPPSARRAPA AATSAPEAPA VRARRAERGH VTDGLAGLVL VGEPEVGKYA
     LAARRRMELL SEASASIGTT LDVLRTAQEL AETAVPGLAD FVTIDLPDAV LRGDEPLDPR
     RDLRRAVIHG IRDDCPFYPV GKRITYHPTT PQLRCVNTGH AVLEPDLKTA AGWLIQDPEH
     TTRLLSHVRS LIAVPLVARG TVLGIVSFYR SLDPAPFGDD DRSLAQELAT RAALSMDNAR
     RYTREHNMVL ALQHSLLPHG VPGQDAVEVA HRYLPAESRV GGDWYDIIPL PGTRVGLVVG
     DVVGHGMHSA ATMGRLRTAA RSFAELDFPP DEVLTHLDNL VLRLDREESS EGSGDGFGII
     GATCLYVVYD PTSQRCAMAR AGHPPPALVR PDGTVSFPDL PAGPPLGLGG LPFETAEIEV
     SEGSQLVLYT DGLIEDRHRG IDVALDRLRA VLAHPQRTPE DTCQAVLDDV APVHPCDDIA
     VLVARTHAFD ADRVATWELP TDPAVVPEIR AAADRQLADW GRGEVAFVAE LLLSELVTNA
     LRHASGPIKV RLLHSRTLIC EVSDTSSTAP HLRRAATTDE DGRGLFLVAQ LALSWGTRHT
     PDGKVIWAEC PLGTP
//