ID D9WUI6_9ACTN Unreviewed; 353 AA.
AC D9WUI6;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=LacI-family transcriptional regulator {ECO:0000313|EMBL:EFL26368.1};
GN ORFNames=SSOG_06082 {ECO:0000313|EMBL:EFL26368.1};
OS Streptomyces himastatinicus ATCC 53653.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group.
OX NCBI_TaxID=457427 {ECO:0000313|EMBL:EFL26368.1, ECO:0000313|Proteomes:UP000003963};
RN [1] {ECO:0000313|EMBL:EFL26368.1, ECO:0000313|Proteomes:UP000003963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53653 {ECO:0000313|EMBL:EFL26368.1,
RC ECO:0000313|Proteomes:UP000003963};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Microbial Sequencing Center;
RA Fischbach M., Godfrey P., Ward D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Bochicchio J., Borenstein D., Chapman S.B.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Richards J.,
RA Roberts A., Saif S., Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S.N.,
RA Thomson T., Walk T., White J., Yandava C., Straight P., Clardy J., Hung D.,
RA Kolter R., Mekalanos J., Walker S., Walsh C.T., Wieland-Brown L.C.,
RA Haas B., Nusbaum C., Birren B.;
RT "Annotation of Streptomyces hygroscopicus strain ATCC 53653.";
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG657754; EFL26368.1; -; Genomic_DNA.
DR AlphaFoldDB; D9WUI6; -.
DR STRING; 457427.SSOG_06082; -.
DR HOGENOM; CLU_037628_6_1_11; -.
DR Proteomes; UP000003963; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR001761; Peripla_BP/Lac1_sug-bd_dom.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF138; HTH-TYPE TRANSCRIPTIONAL REGULATOR KDGR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF00532; Peripla_BP_1; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 27..81
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 353 AA; 37889 MW; 30925CD94B9FE5CA CRC64;
MAMKPLSDTQ SPHREGHTMP GRAEQRVTLR DVAKAAGVST ATVTRTLQNS PRVEPETRRR
VMEQVQLLGY SPNPIARDLR YGRREAAVGL VTAGFTNLFQ AGVASGAERE LRHAGLQLII
GSTDDTPARE PELARAMIDR RVSALLMMPD GDHRDFLSPE HTHGTPVVLV GRPAADLAAD
VVMTDDDHAV QQATQHLIGL GHHRIAALTG RLDSFRATQR LGGYRSALAE SGVREEPPLV
VGDLTTPQQA REAVVRLLDL PSPPTAVLAL NLGISTGVLI ERLAGQHAFA FIGLDETDVS
KGLGVSAVVR DPQEVGRQAA RLAIDRIATP DRPPRTVTVP SAFVRRGTGE VGP
//
