ID DENR_PICGU Reviewed; 201 AA.
AC A5DGV3;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 24-JAN-2024, entry version 65.
DE RecName: Full=Translation machinery-associated protein 22;
GN Name=TMA22; ORFNames=PGUG_02504;
OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX NCBI_TaxID=294746;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBUNIT: Interacts with the 40S ribosomal subunit. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- DOMAIN: The SUI1 domain may be involved in RNA binding.
CC -!- SIMILARITY: Belongs to the DENR family. {ECO:0000305}.
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DR EMBL; CH408157; EDK38406.1; -; Genomic_DNA.
DR RefSeq; XP_001484775.1; XM_001484725.1.
DR AlphaFoldDB; A5DGV3; -.
DR SMR; A5DGV3; -.
DR STRING; 294746.A5DGV3; -.
DR GeneID; 5126840; -.
DR KEGG; pgu:PGUG_02504; -.
DR eggNOG; KOG3239; Eukaryota.
DR HOGENOM; CLU_073511_0_1_1; -.
DR InParanoid; A5DGV3; -.
DR OMA; EVFEIDM; -.
DR OrthoDB; 130735at2759; -.
DR Proteomes; UP000001997; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR CDD; cd11607; DENR_C; 1.
DR Gene3D; 3.30.780.10; SUI1-like domain; 1.
DR InterPro; IPR046447; DENR_C.
DR InterPro; IPR005873; DENR_eukaryotes.
DR InterPro; IPR048517; DENR_N.
DR InterPro; IPR001950; SUI1.
DR InterPro; IPR036877; SUI1_dom_sf.
DR NCBIfam; TIGR01159; DRP1; 1.
DR PANTHER; PTHR12789:SF0; DENSITY-REGULATED PROTEIN; 1.
DR PANTHER; PTHR12789; DENSITY-REGULATED PROTEIN HOMOLOG; 1.
DR Pfam; PF21023; DENR_N; 1.
DR Pfam; PF01253; SUI1; 1.
DR SUPFAM; SSF55159; eIF1-like; 1.
DR PROSITE; PS50296; SUI1; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..201
FT /note="Translation machinery-associated protein 22"
FT /id="PRO_0000320448"
FT DOMAIN 94..165
FT /note="SUI1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00200"
SQ SEQUENCE 201 AA; 22626 MW; 8C90486BDBC57DA1 CRC64;
MTEVEPKSVL YCGVCSFPPE FCEFGGSFKR CKEWLEQNDK ELYEKLYSED ALANATSTLS
IDKEQKIAKE LEKKQAKEEA KQERELKKQL ASKVTIKRIE RNKRKHVIAI SGLEVFDIDM
KKLSKTFASK FATGASVTKN AEKKDEIIVQ GDVSDEARAY IEKLLEEKGL NEVKVEQIDD
KKKKKAAEAA EAAAAATGNK K
//
