ID E0CQJ8_VITVI Unreviewed; 471 AA.
AC E0CQJ8;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Dehydrogenase E1 component domain-containing protein {ECO:0000259|Pfam:PF00676};
GN OrderedLocusNames=VIT_18s0001g14980 {ECO:0000313|EMBL:CBI19927.3};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CBI19927.3, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FN595227; CBI19927.3; -; Genomic_DNA.
DR RefSeq; XP_002268860.1; XM_002268824.3.
DR AlphaFoldDB; E0CQJ8; -.
DR STRING; 29760.E0CQJ8; -.
DR PaxDb; 29760-VIT_18s0001g14980-t01; -.
DR EnsemblPlants; Vitvi18g01174_t001; Vitvi18g01174_P001; Vitvi18g01174.
DR GeneID; 100245451; -.
DR Gramene; Vitvi18g01174_t001; Vitvi18g01174_P001; Vitvi18g01174.
DR KEGG; vvi:100245451; -.
DR eggNOG; KOG1182; Eukaryota.
DR HOGENOM; CLU_029393_1_2_1; -.
DR InParanoid; E0CQJ8; -.
DR OMA; DWHTGYD; -.
DR OrthoDB; 952at2759; -.
DR Proteomes; UP000009183; Chromosome 18.
DR GO; GO:0005947; C:mitochondrial alpha-ketoglutarate dehydrogenase complex; IBA:GO_Central.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR GO; GO:0009083; P:branched-chain amino acid catabolic process; IBA:GO_Central.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR43380; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43380:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183}.
FT DOMAIN 136..430
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
SQ SEQUENCE 471 AA; 52830 MW; CA21F8A9DD298660 CRC64;
MAAWFTRSGN IAHHVKRNMG SFLRPAPTLS DSSWSRSPAC LGNSPALLWA GRLESTRAQK
LVDSDSENDA PLRDDDQAID FPGGRVMLTS EMQFIPGYPQ QRVHCYHLMN NDGQTNMCSS
FEQVSKEVAV KMYSDMITLQ IMDTIFYEAQ RQGRISFYLT SVGEEAINIA SAAALSPDDI
VMAQYREPGV LLWRGFTLQE FANQCFGNKA DCGKGRQMPI HYGSKKLNYF TVSSPLATQL
PQAVGAAYSL KMDNKDACVV AYFGDGSTSE GDFHASLNFA AVMEAPVIFL CRNNGWAIST
PTSEQFRSDG IVVKGPAYGI QSIRVDGNDA LAVHNAVRAA RQMAIHEQRP ILVEALTYRV
GHHSTSDDST KYRPVDEVKH WEMGQNPVNR FRKWVERNGW WSEEDESQLR SSIRKQLLQA
IQVAEKMEKP PLADLFSDVY DVPPSILFEQ EQQLRETIKR HPQDYPSDVP V
//
