ID E0CW81_ORYMI Unreviewed; 379 AA.
AC E0CW81;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Alcohol dehydrogenase family-2 {ECO:0000313|EMBL:ACS49615.1};
GN ORFNames=OM_Ba158E13_111D20.3 {ECO:0000313|EMBL:ACS49615.1};
OS Oryza minuta.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=63629 {ECO:0000313|EMBL:ACS49615.1};
RN [1] {ECO:0000313|EMBL:ACS49615.1}
RP NUCLEOTIDE SEQUENCE.
RA Ammiraju J.S.S., Lu F., Sanyal A., Song X., Jiang N., Pontaroli A.C.,
RA Rambo T., Currie J., Kollura K., Talag J., Fan C., Goicoechea J.L.,
RA Zuccolo A., Bennetzen J.L., Chen M., Jackson S., Wing R.A.;
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACS49615.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20487382;
RA Ammiraju J.S., Fan C., Yu Y., Song X., Cranston K.A., Pontaroli A.C.,
RA Lu F., Sanyal A., Jiang N., Rambo T., Currie J., Collura K., Talag J.,
RA Bennetzen J.L., Chen M., Jackson S., Wing R.A.;
RT "Spatio-temporal patterns of genome evolution in allotetraploid species of
RT the genus Oryza.";
RL Plant J. 63:430-442(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH;
CC Xref=Rhea:RHEA:10736, ChEBI:CHEBI:15378, ChEBI:CHEBI:15734,
CC ChEBI:CHEBI:17478, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001146};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a secondary alcohol + NAD(+) = a ketone + H(+) + NADH;
CC Xref=Rhea:RHEA:10740, ChEBI:CHEBI:15378, ChEBI:CHEBI:17087,
CC ChEBI:CHEBI:35681, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000781};
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
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DR EMBL; GQ203299; ACS49615.1; -; Genomic_DNA.
DR AlphaFoldDB; E0CW81; -.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08301; alcohol_DH_plants; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43880; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR43880:SF62; ALCOHOL DEHYDROGENASE 2; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 36..121
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 205..337
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
SQ SEQUENCE 379 AA; 41141 MW; 3AFDEE35AC0EA6A4 CRC64;
MATAGKVIKC KAAVAWEAGK PLSIEEVEVA PPQAMEVRVK ILYTALCHTD VYFWEAKGQT
PVFPRILGHE AGGIVESVGE GVTELAPGDH VLPVFTGECK ECAHCKSEES NMCDLLRINV
DRGVMIGDGQ SRFTIKGKPI FHFVGTSTFS EYTVIHVGCL AKINPEAPLD KVCILSCGIS
TGLGATLNVA KPKKGQTVAI FGLGAVGLAA MEGARLSGAS RIIGVDLNPA KFEQAKKFGC
TDFVNPKDHS KPVHEVLIEM TNGGVDRAVE CTGNINAMIS CFECVHDGWG VAVLVGVPTK
DDVFKTHPMN FLNEKTLKGT FFGNYKPRTD LPNVVEMYMK KELELEKFIT HSVPFSEINT
AFDLMLKGES LRCIMRMEE
//
