ID E0CX25_MOUSE Unreviewed; 157 AA.
AC E0CX25;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Solute carrier organic anion transporter family, member 1a5 {ECO:0000313|Ensembl:ENSMUSP00000124987.2};
DE Flags: Fragment;
GN Name=Slco1a5 {ECO:0000313|Ensembl:ENSMUSP00000124987.2,
GN ECO:0000313|MGI:MGI:1351865};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000124987.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000124987.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000124987.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000124987.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000124987.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; E0CX25; -.
DR SMR; E0CX25; -.
DR jPOST; E0CX25; -.
DR MaxQB; E0CX25; -.
DR PeptideAtlas; E0CX25; -.
DR ProteomicsDB; 322286; -.
DR Ensembl; ENSMUST00000128446.2; ENSMUSP00000124987.2; ENSMUSG00000063975.14.
DR AGR; MGI:1351865; -.
DR MGI; MGI:1351865; Slco1a5.
DR VEuPathDB; HostDB:ENSMUSG00000063975; -.
DR GeneTree; ENSGT01080000257336; -.
DR HOGENOM; CLU_008954_0_3_1; -.
DR OMA; DCNMDCN; -.
DR ChiTaRS; Slco1a5; mouse.
DR Proteomes; UP000000589; Chromosome 6.
DR Bgee; ENSMUSG00000063975; Expressed in seminal vesicle and 43 other cell types or tissues.
DR ExpressionAtlas; E0CX25; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004156; OATP.
DR PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR PANTHER; PTHR11388:SF148; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER-RELATED; 1.
DR Pfam; PF03137; OATP; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..157
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT NON_TER 157
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000124987.2"
SQ SEQUENCE 157 AA; 17530 MW; 45F95EF35C19F40B CRC64;
MLTQIERQFD IPTSIVGLIN GSFEIGNLLL IILVSYFGTK LHRPIMIGIG CVIMGLGCFL
MSLPHFLMGR YEYETTISPT SNLSSNSFLC MENRTQTLKP TQDPAECVKE MKSLMWIYVL
VGNIIRGIGE TPIMPLGISY IEDFAKSENS PLYIGIL
//
