ID   E0D412_ORITS            Unreviewed;       116 AA.
AC   E0D412;
DT   02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=Malate dehydrogenase {ECO:0000256|ARBA:ARBA00020382};
DE            EC=1.1.1.37 {ECO:0000256|ARBA:ARBA00012995};
DE   Flags: Fragment;
GN   Name=mdh {ECO:0000313|EMBL:BAJ16283.1};
OS   Orientia tsutsugamushi (Rickettsia tsutsugamushi).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Orientia.
OX   NCBI_TaxID=784 {ECO:0000313|EMBL:BAJ16283.1};
RN   [1] {ECO:0000313|EMBL:BAJ16283.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Gilliam {ECO:0000313|EMBL:BAJ16283.1};
RA   Nakayama K., Kurokawa K., Fukuhara M., Urakami H., Yamamoto S.,
RA   Yamazaki K., Ogura Y., Ooka T., Hayashi T.;
RT   "Genome Comparison and Phylogenetic Analysis of Orientia tsutsugamushi
RT   Strains.";
RL   DNA Res. 17:281-291(2010).
RN   [2] {ECO:0000313|EMBL:BAP28440.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Ot98 {ECO:0000313|EMBL:BAP28440.1};
RA   Chiba K., Kitakawa K., Suzuki R., Kashiwagi Y., Kanari A., Yoshida M.;
RT   "Morecular epidemiology of Orientia tsutsugamushi.";
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the reversible oxidation of malate to oxaloacetate.
CC       {ECO:0000256|ARBA:ARBA00003966}.
CC   -!- SIMILARITY: Belongs to the LDH/MDH superfamily. MDH type 1 family.
CC       {ECO:0000256|ARBA:ARBA00008824}.
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DR   EMBL; AB537283; BAJ16283.1; -; Genomic_DNA.
DR   EMBL; AB982112; BAP28440.1; -; Genomic_DNA.
DR   AlphaFoldDB; E0D412; -.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001236; Lactate/malate_DH_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR11540; MALATE AND LACTATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11540:SF16; MALATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   Pfam; PF00056; Ldh_1_N; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
FT   DOMAIN          1..115
FT                   /note="Lactate/malate dehydrogenase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00056"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:BAJ16283.1"
FT   NON_TER         116
FT                   /evidence="ECO:0000313|EMBL:BAJ16283.1"
SQ   SEQUENCE   116 AA;  12487 MW;  03937557278A2AC3 CRC64;
     LAHLIAVKEL GDVVIVDKTK AVAQGKALDI SQSMGIGKSC INITGTNNYQ EIQDSNVVIV
     TAGIARKPGM SRNDLVNTNA QIMIDIATQI KYYSSNALVI VVTNPLDAMV WVMQKN
//