ID E0DBY0_9CORY Unreviewed; 508 AA.
AC E0DBY0;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=Catalase {ECO:0000313|EMBL:EFM50213.1};
DE EC=1.11.1.6 {ECO:0000313|EMBL:EFM50213.1};
GN ORFNames=HMPREF0299_5824 {ECO:0000313|EMBL:EFM50213.1};
OS Corynebacterium matruchotii ATCC 14266.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=553207 {ECO:0000313|EMBL:EFM50213.1, ECO:0000313|Proteomes:UP000004218};
RN [1] {ECO:0000313|EMBL:EFM50213.1, ECO:0000313|Proteomes:UP000004218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14266 {ECO:0000313|EMBL:EFM50213.1,
RC ECO:0000313|Proteomes:UP000004218};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|PIRSR:PIRSR038928-2};
CC -!- SIMILARITY: Belongs to the catalase family.
CC {ECO:0000256|ARBA:ARBA00005329}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFM50213.1}.
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DR EMBL; ACSH02000002; EFM50213.1; -; Genomic_DNA.
DR AlphaFoldDB; E0DBY0; -.
DR STRING; 553207.HMPREF0299_5824; -.
DR eggNOG; COG0753; Bacteria.
DR OrthoDB; 3169619at2; -.
DR Proteomes; UP000004218; Unassembled WGS sequence.
DR GO; GO:0004096; F:catalase activity; IEA:UniProtKB-EC.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR Gene3D; 2.40.180.10; Catalase core domain; 1.
DR InterPro; IPR018028; Catalase.
DR InterPro; IPR024711; Catalase_clade1/3.
DR InterPro; IPR011614; Catalase_core.
DR InterPro; IPR002226; Catalase_haem_BS.
DR InterPro; IPR010582; Catalase_immune_responsive.
DR InterPro; IPR020835; Catalase_sf.
DR PANTHER; PTHR11465; CATALASE; 1.
DR PANTHER; PTHR11465:SF9; CATALASE; 1.
DR Pfam; PF00199; Catalase; 1.
DR Pfam; PF06628; Catalase-rel; 1.
DR PIRSF; PIRSF038928; Catalase_clade1-3; 1.
DR PRINTS; PR00067; CATALASE.
DR SMART; SM01060; Catalase; 1.
DR SUPFAM; SSF56634; Heme-dependent catalase-like; 1.
DR PROSITE; PS00437; CATALASE_1; 1.
DR PROSITE; PS51402; CATALASE_3; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|PIRSR:PIRSR038928-2};
KW Hydrogen peroxide {ECO:0000256|ARBA:ARBA00023324};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR038928-2};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR038928-2};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EFM50213.1};
KW Peroxidase {ECO:0000256|ARBA:ARBA00022559, ECO:0000313|EMBL:EFM50213.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004218}.
FT DOMAIN 18..403
FT /note="Catalase core"
FT /evidence="ECO:0000259|SMART:SM01060"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 67
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-1"
FT ACT_SITE 139
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-1"
FT BINDING 349
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-2"
SQ SEQUENCE 508 AA; 57262 MW; 32AF4C5954D07EE7 CRC64;
MNTNDIVTNG MGPELTGTTH QHGGRPVASE NVSITAGPQG ATVLNDIHLV EKLAHFNRER
VPERNPHAKG HGAFGELHIT HDVSAYTKAQ LFQPNTVTPV AVRFSTVAGE QGSPDTWRDV
HGFAVRFYTE EGNFDIVGNN TPTFFLRDGM KFPDFIHSQK RMGPTGLRSA DAQWDFWTRT
PESAHQVTYL MGDRGTPKTS RHQDGFGSHT FQWLNAKGEA FWVKYHFKTR QGWDCFTDEE
AQEMAGKNAD YQREDLFNAI ERGDYPIWDV KVQIMPFAEA ETYRYNPFDL TKTWSHKDYP
LIDVGYFVLN RNPVNYFAQI EQLAFDPANL VPGVGLSPDR MLMARAFAYA DAHRYRIGPN
YRQLPVNQPV HPVNTYAHQG PMAYQFNPAS APVYTPNRFD KGAGYLDDGV SSNSGYGAAD
ELFINPDPHG TDLGRAPYVA HPEDDDFGQA GILYREVMDD GAKDRLAHNI TNAMVGVSPE
TEQRCYWYWD QVDPQLGAEV RKRFAAKK
//
