ID E0DFU1_9CORY Unreviewed; 713 AA.
AC E0DFU1;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=HD domain-containing protein {ECO:0000259|PROSITE:PS51831};
GN ORFNames=HMPREF0299_6735 {ECO:0000313|EMBL:EFM48702.1};
OS Corynebacterium matruchotii ATCC 14266.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=553207 {ECO:0000313|EMBL:EFM48702.1, ECO:0000313|Proteomes:UP000004218};
RN [1] {ECO:0000313|EMBL:EFM48702.1, ECO:0000313|Proteomes:UP000004218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14266 {ECO:0000313|EMBL:EFM48702.1,
RC ECO:0000313|Proteomes:UP000004218};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFM48702.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ACSH02000005; EFM48702.1; -; Genomic_DNA.
DR RefSeq; WP_005525957.1; NZ_ACSH02000005.1.
DR AlphaFoldDB; E0DFU1; -.
DR STRING; 553207.HMPREF0299_6735; -.
DR GeneID; 84574186; -.
DR eggNOG; COG2844; Bacteria.
DR OrthoDB; 9758038at2; -.
DR Proteomes; UP000004218; Unassembled WGS sequence.
DR GO; GO:0008773; F:[protein-PII] uridylyltransferase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR InterPro; IPR005105; GlnD_Uridyltrans_N.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR010043; UTase/UR.
DR PANTHER; PTHR47320; BIFUNCTIONAL URIDYLYLTRANSFERASE/URIDYLYL-REMOVING ENZYME; 1.
DR PANTHER; PTHR47320:SF1; BIFUNCTIONAL URIDYLYLTRANSFERASE_URIDYLYL-REMOVING ENZYME; 1.
DR Pfam; PF03445; DUF294; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR PROSITE; PS51831; HD; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Reference proteome {ECO:0000313|Proteomes:UP000004218};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 389..490
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 713 AA; 78121 MW; 928DD39F8076F688 CRC64;
MPQPAADIRR TAFRRATELV AALHLPHGTA LAATGSYARR ELTAHSDLDL LLICPPDQAL
DSAVKHQVEN LWYPIWDAKI RLDYAVRTPE ECANIIADNA VAGLSLLDLT HVAGNPSLTE
QTRKLVLRTW RIALSRNFDN IIDIAIARWR RSGPVVSMTH PDLKHGRGGL RDHELLTALA
FGNLCDAPDL TDQRTLLLDT RTMLHQHARR SRDVLDPEFA ADIAIDLGFR DRYALSRAIA
EAARAIDDAL TSGLTTARNL LRPTTPTSLK PERRRPLDID VVDAGGSVSL SRNPNLTDPA
LLLRVAAASA RTGLPIHPAT WSRLAALPPM PDRWPAAAAS DFLALLSSPH HTARVITELD
NHGLWSPLVP AWDNIRGLIP REPIHTQTID QHCLQVTQNC AAHHVAAARP DLLYLAALFH
DIGKGQGVPH AELGATRVAV MAATLRLNHH DASVVTTLVR HHTLIPNLVA HRDVESDDAV
TELLDAVGYD LLTVELMRVL VQADALATGT WTPTLRAGTA ILCDRARARL TGSQPRPPRL
DFPHDFTSRA GLPLDLIPGP EANNATVRWV GHYLRESIRV LALIAAKGWN INSAEFIVEP
DHTRARFTVY NTLGTGFDQA EFAQAYKSGV YSALPDTTPT IAATTATFWF GNILEIRTTD
RQAALGTLME VLPELHWLTM SNPGATMIVQ CSLRPGFDRA AVERDVTRVL TTS
//
