ID E0E1W6_9FIRM Unreviewed; 1997 AA.
AC E0E1W6;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Leucine Rich Repeat protein {ECO:0000313|EMBL:EFM65116.1};
GN ORFNames=HMPREF0634_1460 {ECO:0000313|EMBL:EFM65116.1};
OS Peptostreptococcus stomatis DSM 17678.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC Peptostreptococcus.
OX NCBI_TaxID=596315 {ECO:0000313|EMBL:EFM65116.1, ECO:0000313|Proteomes:UP000003244};
RN [1] {ECO:0000313|EMBL:EFM65116.1, ECO:0000313|Proteomes:UP000003244}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17678 {ECO:0000313|EMBL:EFM65116.1,
RC ECO:0000313|Proteomes:UP000003244};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Nelson K.E.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFM65116.1}.
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DR EMBL; ADGQ01000025; EFM65116.1; -; Genomic_DNA.
DR RefSeq; WP_007788616.1; NZ_ADGQ01000025.1.
DR STRING; 596315.HMPREF0634_1460; -.
DR GeneID; 84801529; -.
DR eggNOG; COG3266; Bacteria.
DR eggNOG; COG4886; Bacteria.
DR eggNOG; COG5386; Bacteria.
DR Proteomes; UP000003244; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd06920; NEAT; 1.
DR Gene3D; 2.60.40.1850; -; 2.
DR Gene3D; 3.40.50.12090; -; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR007253; Cell_wall-bd_2.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR006635; NEAT_dom.
DR InterPro; IPR037250; NEAT_dom_sf.
DR PANTHER; PTHR45712; AGAP008170-PA; 1.
DR PANTHER; PTHR45712:SF22; LEUCINE RICH REPEAT FAMILY PROTEIN; 1.
DR Pfam; PF04122; CW_binding_2; 3.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00364; LRR_BAC; 4.
DR SMART; SM00369; LRR_TYP; 8.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF158911; NEAT domain-like; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS51450; LRR; 3.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000003244};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..1997
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039483525"
FT DOMAIN 806..841
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 173..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 323..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 323..341
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..356
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1997 AA; 223123 MW; 9F2A817E20C6F63D CRC64;
MKYWKKSGKK GKKFVTVALS LAMLGTTTAP TMHILGQSIG SAYADEVVEE NIWDYISIRI
AEYGDTHPIK FISKKDEAGQ EVINKWYNKI DKVIINGTEF DFSEFEDVRN DLSKKWTADY
QSKDDKWQAH ANAFNLKPST DVVIGIKMKG SGDIHELDYK SGTNDQVSRI IKGSGKDVTP
ADDENKNPGN NTGGTETDPG KNEKIGIPTE EFNKVLVADG KVKVQFKYDS DRARKKVKMD
GYYKNMTSVE INGENFPIDE FTFTTEPAWD YGDLHSKPEY FEKHKAALNK YGEEGNKYKL
VIKLKDGKTG IYESDQYKIA VKSGEIKEEQ KETEKPNDDT KVNPPTNDTD TSGYTKNRTI
YTKNANQRSL ETTVYGIRPL NADKDKGVSI DMFSVSMDTS ITNYKLQVLS RIKSISVDGT
TIQNEGDIKQ VDEEVDEYTN WNLKFDKRFS FIKRNSREGE NRVLREFTIK DENLLNAYNK
VEEKKGNHRF AIEFVDGSTL KYETPDKKPE GMTWAQFYKD AIKEVKRREQ SIIINLKGYE
EKSDAELQEH RSLVYGLAPH IKQVIINGYT VQDDKFLKNS GGNDFMNEPN GNDDPIIKNW
NSDVGAKNKV EFFLDDNSTI TWSDNVKEEE DVELPQEEAK ELEGLKKIDI ADLEKSPDGK
YTIGFEAKYA DGRKGTSMLQ GFFDRNVEIE KRGDKITARF LNLFFADGLL DFRIKNTDNT
WPEESKKDFV DPATKTQAYF TMDLKDLTKA REGAVLVSYM GGKLEYKGMM DTKYTKVKIV
FKKDAYVGWK GFHETYDLEQ KRKLSSEILK NRLTFSGLDR DNNGEISSDE LQKAPAVVDL
TWRGAPLERQ FNSIYDISIL KDLGPNVKVI KLSSNSLKSL PAGVFDKAVN LEEIYLNGNK
IADLPKDIFK NNKKLKKVSL ASNPLAVLDK DLFANNPEIT DLDLGNTLLS EVKEGTFDKL
EKLRNLSLSA NDLSILPDSL FKNNKELRIL SITDNALVKL PSSLSSASNL ENLGLGNNRL
TNLPDYVGEF ASLKQLDLKF NNISKISEDT WKNLAKRDGL KIDLIHNNLT SLPSLEDVKF
ASLDVAANML PAEIPDSYKA LKIGEKNQGG YYAQRSPVDY NITAKNGKVE FSNKKDMNIL
DLLNWNEAVT HENKSVFKMS EYKAYADKLL KKNGGEYEDI ASKLRKTRDF KVVTRIERVY
DDGSTKTIFE KEDLNKLEGA LETANDKRME NGNRYRLTQQ LYTLVVGEWV KNYEVNKEVT
ATVDANANPG SGSPENDNTK KVLKYTLPVN LVKYDNRSEN SMGADAMDKT VQVEETSKGV
KFTLNFHSME YVLAGKKRIG HLYKMGVYDA VDEATGNDYV PANVLSKYED AGSEFPGKVS
FTRTKRGEKE IAVRVWVDAM DAIAKETGNA NQDASQPAIL SIDWSNAPKE SLIGKEEGNK
TDNNDKNEDS VSKKALLKNS IKMAEKMLKS GLVEGRSKEI LEKAIENARK VYNSDKKESF
ESANDIIMFA LDNIKKESGS KDGDQVKNSA DIKQLDKDIA EKENKNGAKL YSVPVKLWHA
TDSKESMGNG AIVKTAIVSE KDGKYTYYVD FTGMPFFGMY GHLWDLNVYE NGLGSSKTPA
RVEKTKMDKD LTGKMREFPA RFSFTRTTKE REIFAEVAVD AMDSMKNNAE TYDKIVKGSG
KQNAKFIFDW SAAKQYKEAD QEVENKVGRL AGADRYETST KISQKYFDRA DTVVLASGKN
TVDALVSASY ADAKKSPILL SKQSDVPASV KAEILRLGAK NVVIVGGNAS ISAKAENELK
AMGLSIRRIA GSSRYETSAI LAQEVRYLTG SDKLILITGQ DNKEADALTV SSIATKSGIP
VMMTKANELD SNARAKINSW KPSEVIVIGG KSTISDGVMN QINAKSKTRI AGATRFETAA
MIAKEAYPSS KHVFVTNGYK AVDALAAGAV TGRAKSPIVL VGSNSVTSDV KKLASGKQIT
TLGGSSTVSD KIVDELK
//
