ID   E0J2H5_ECOLW            Unreviewed;       551 AA.
AC   E0J2H5;
DT   02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 72.
DE   SubName: Full=Trehalose-6-P hydrolase {ECO:0000313|EMBL:ADT77876.1};
GN   Name=treC {ECO:0000313|EMBL:ADT77876.1};
GN   OrderedLocusNames=ECW_m4600 {ECO:0000313|EMBL:ADT77876.1};
OS   Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / LMG 11080 / NBRC
OS   13500 / NCIMB 8666 / NRRL B-766 / W).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=566546 {ECO:0000313|EMBL:ADT77876.1, ECO:0000313|Proteomes:UP000008525};
RN   [1] {ECO:0000313|EMBL:ADT77876.1, ECO:0000313|Proteomes:UP000008525}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 9637 / CCM 2024 / DSM 1116 / LMG 11080 / NBRC 13500 /
RC   NCIMB 8666 / NRRL B-766 / W {ECO:0000313|Proteomes:UP000008525};
RX   PubMed=21208457; DOI=10.1186/1471-2164-12-9;
RA   Archer C.T., Kim J.F., Jeong H., Park J.H., Vickers C.E., Lee S.Y.,
RA   Nielsen L.K.;
RT   "The genome sequence of E. coli W (ATCC 9637): comparative genome analysis
RT   and an improved genome-scale reconstruction of E. coli.";
RL   BMC Genomics 12:9-9(2011).
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DR   EMBL; CP002185; ADT77876.1; -; Genomic_DNA.
DR   RefSeq; WP_001349991.1; NZ_WBMH01000023.1.
DR   AlphaFoldDB; E0J2H5; -.
DR   KEGG; elw:ECW_m4600; -.
DR   PATRIC; fig|566546.30.peg.4661; -.
DR   Proteomes; UP000008525; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0008788; F:alpha,alpha-phosphotrehalase activity; IEA:InterPro.
DR   GO; GO:0005993; P:trehalose catabolic process; IEA:InterPro.
DR   CDD; cd11333; AmyAc_SI_OligoGlu_DGase; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR022567; DUF3459.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR045857; O16G_dom_2.
DR   InterPro; IPR012769; Trehalose_TreC.
DR   NCBIfam; TIGR02403; trehalose_treC; 1.
DR   PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR10357:SF179; NEUTRAL AND BASIC AMINO ACID TRANSPORT PROTEIN RBAT; 1.
DR   Pfam; PF00128; Alpha-amylase; 1.
DR   Pfam; PF11941; DUF3459; 1.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ADT77876.1}.
FT   DOMAIN          15..414
FT                   /note="Glycosyl hydrolase family 13 catalytic"
FT                   /evidence="ECO:0000259|SMART:SM00642"
SQ   SEQUENCE   551 AA;  63902 MW;  FC00C36C6246C97E CRC64;
     MTNLPHWWQN GVIYQIYPKS FQDTTGSGTG DLRGVIQRLD YLHKLGVDAI WLTPFYISPQ
     VDNGYDVANY TAIDPTYGTL DDFDELVTQA KSRGIRIILD MVFNHTSTQH AWFREALNKE
     SPYRQFYIWR DGEPETPPNN WRSKFGGSAW RWHAESEQYY LHLFAPEQAD LNWENPAVRA
     ELKKVCEFWA DRGVDGLRLD VVNLISKDPR FPEDLDGDGR RFYTDGPRAH EFLHEMNRDV
     FTPRGLMTVG EMSSTSLEHC QRYAALTGSE LSMTFNFHHL KVDYPGGEKW TLAKPDFVAL
     KTLFRHWQQG MHNVAWNALF WCNHDQPRII SRFGDEGEYR VPAAKMLAMV LHGMQGTPYI
     YQGEEIGMTN PHFTRITDYR DVESLNMFAE LRNDGRDADE LLAILASKSR DNSRTPMQWS
     NGDNAGFTAG EPWIGLGDNY QKINVEAALA DESSVFYTYQ KLIALRKQEA ILTWGNYQDL
     LPNSPVLWCY RREWKGQTLL VIANLSREIQ PWQPGQMRGN WQLVMHNYEE ASPQPCAMNL
     RPFEAVWWLQ K
//