ID E0Q9B8_9BIFI Unreviewed; 936 AA.
AC E0Q9B8;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=MMPL family protein {ECO:0000313|EMBL:EFM40841.1};
GN ORFNames=HMPREF0168_1864 {ECO:0000313|EMBL:EFM40841.1};
OS Bifidobacterium dentium ATCC 27679.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=871562 {ECO:0000313|EMBL:EFM40841.1, ECO:0000313|Proteomes:UP000003323};
RN [1] {ECO:0000313|EMBL:EFM40841.1, ECO:0000313|Proteomes:UP000003323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27679 {ECO:0000313|EMBL:EFM40841.1,
RC ECO:0000313|Proteomes:UP000003323};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFM40841.1}.
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DR EMBL; AEEQ01000011; EFM40841.1; -; Genomic_DNA.
DR AlphaFoldDB; E0Q9B8; -.
DR HOGENOM; CLU_005108_1_3_11; -.
DR Proteomes; UP000003323; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 184..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 528..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 562..579
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 599..620
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 641..663
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 675..700
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 200..333
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 936 AA; 100134 MW; 13867DA05C4206ED CRC64;
MSFSLYKLGQ LMVRRHGRVL MAWLLALVLA VAGMATLAHG TNDEFSIPGS QSQDALDHLG
HVFPEVSGTS AQIVAVAPES QRIDTTESRN AIGVVAKRIG GYRQVTLAAD PFSETVQDAV
SEDGRAAIIA IQFEVPFNEL DSQVKSKIAS DAKALQDALM DGAVTYCGGA AYRNAIPSLS
PTEALGLAFA LIALLMMFGS LVAAVLPLFT AVVGVGVGVA TIYTMTSWFT ISSTAPMLAV
MIGLAVGIDY ALFLISRHRD QLSDGLEVEE SIARSVATAG SAVIFAGLTV IIALLGLFVA
GIPFLTTMGV AAAFGVLVAV TVAETLVPAL LGFAGKRLIP RKRANVKTSR RSLTNRKSHD
RRIARTWVRL VTAKPLAVVV VITVALSALA LPAANLRLAL PDNSVEEIGT PARDAYDAVA
EHFGPGFNGP LILTADIIQS TDPIGLANRI ADDIRRLPGV KAVPLATPNP KGDTGIIQIV
PETGPSDAAT EQLVRELRGK YQYFLDTYDT ETAVTGITAV AIDVSSKLGA ALLPFGLLVV
GLSLILLAMV FRSIWVPLKA TAGYLLSVLA AFGVTTWVFQ LGHGAELIRV QRVGPVISFL
PIILMGVLFG LAMDYEVFLV SRIREHYAHH GDAKAAVEEG FASASTVVVA AATIMLSVFA
AFIPEGSATI KPIAFSLAVG MFVDAFVVRL TLVPAVLALL GKRAWHLPAW VDRRLPVFDA
EGDGLERELR LRDWPTPDST EVLSAHDLTL DDMNGNALYE HIDLHIKPGE VLVVEDSGVS
GKSALLYTLA GRVTTFRGDL KVIGCTLPQH MREIRSNVAL ISCANAADPL EDMRQATNDG
TRLIMLNDAD MVLQPDARAQ LRDAISKRGE TTYVLSCRNL STLGDILHGM PLTILRLSSR
TRDSERTDQF DRPESHITRF ARFINSPITT STHVEQ
//
