ID   E0RJQ0_PAEP6            Unreviewed;       179 AA.
AC   E0RJQ0;
DT   02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2010, sequence version 1.
DT   27-MAR-2024, entry version 59.
DE   SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:ADM70019.1};
GN   OrderedLocusNames=PPE_02186 {ECO:0000313|EMBL:ADM70019.1};
OS   Paenibacillus polymyxa (strain E681).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=349520 {ECO:0000313|EMBL:ADM70019.1, ECO:0000313|Proteomes:UP000002227};
RN   [1] {ECO:0000313|EMBL:ADM70019.1, ECO:0000313|Proteomes:UP000002227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E681 {ECO:0000313|EMBL:ADM70019.1,
RC   ECO:0000313|Proteomes:UP000002227};
RX   PubMed=20851896; DOI=10.1128/JB.00983-10;
RA   Kim J.F., Jeong H., Park S.Y., Kim S.B., Park Y.K., Choi S.K., Ryu C.M.,
RA   Hur C.G., Ghim S.Y., Oh T.K., Kim J.J., Park C.S., Park S.H.;
RT   "Genome sequence of the polymyxin-producing plant-probiotic rhizobacterium
RT   Paenibacillus polymyxa E681.";
RL   J. Bacteriol. 192:6103-6104(2010).
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DR   EMBL; CP000154; ADM70019.1; -; Genomic_DNA.
DR   RefSeq; WP_013310175.1; NZ_CP048794.1.
DR   AlphaFoldDB; E0RJQ0; -.
DR   KEGG; ppy:PPE_02186; -.
DR   eggNOG; COG1827; Bacteria.
DR   HOGENOM; CLU_108798_0_0_9; -.
DR   Proteomes; UP000002227; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0036094; F:small molecule binding; IEA:InterPro.
DR   Gene3D; 3.30.1340.20; 3H domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR035922; 3H_dom_sf.
DR   InterPro; IPR004173; 3H_domain.
DR   InterPro; IPR013196; HTH_11.
DR   InterPro; IPR026043; NadR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR40068; TRANSCRIPTION REPRESSOR NIAR-RELATED; 1.
DR   PANTHER; PTHR40068:SF1; TRANSCRIPTION REPRESSOR NIAR-RELATED; 1.
DR   Pfam; PF02829; 3H; 1.
DR   Pfam; PF08279; HTH_11; 1.
DR   PIRSF; PIRSF037847; NiaR; 1.
DR   SUPFAM; SSF75500; Putative transcriptional regulator TM1602, C-terminal domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR037847-1};
KW   Nickel {ECO:0000256|PIRSR:PIRSR037847-1}.
FT   DOMAIN          12..64
FT                   /note="Helix-turn-helix type 11"
FT                   /evidence="ECO:0000259|Pfam:PF08279"
FT   DOMAIN          80..176
FT                   /note="3H"
FT                   /evidence="ECO:0000259|Pfam:PF02829"
FT   BINDING         84
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         92
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         151
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
FT   BINDING         153
FT                   /ligand="Ni(2+)"
FT                   /ligand_id="ChEBI:CHEBI:49786"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037847-1"
SQ   SEQUENCE   179 AA;  19840 MW;  16F0D88AD651B251 CRC64;
     MTESLKRSGT DRREQLLLWL KSESPLTGSE LARRSSVSRQ VIVQDISLLK ASQEPILATS
     QGYIYMEPAS QATPLASRII VCKHRPEQTE EELKLIVDYG VSVQDVIVEH PVYGDLTAPI
     RVGTRKEVDD FIRKISSTQA TYLSQLTGGI HLHTLNASNE DKINDACAAL EQAGFLMTD
//