ID E0SAE6_ENCIT Unreviewed; 453 AA.
AC E0SAE6;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=AAA ATPase proteasome regulatory subunit YTA6 {ECO:0000313|EMBL:ADM12571.1};
GN ORFNames=Eint_110710 {ECO:0000313|EMBL:ADM12571.1};
OS Encephalitozoon intestinalis (strain ATCC 50506) (Microsporidian parasite)
OS (Septata intestinalis).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC Encephalitozoon.
OX NCBI_TaxID=876142 {ECO:0000313|EMBL:ADM12571.1, ECO:0000313|Proteomes:UP000002313};
RN [1] {ECO:0000313|EMBL:ADM12571.1, ECO:0000313|Proteomes:UP000002313}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50506 {ECO:0000313|EMBL:ADM12571.1,
RC ECO:0000313|Proteomes:UP000002313};
RX PubMed=20865802; DOI=10.1038/ncomms1082;
RA Corradi N., Pombert J.-F., Farinelli L., Didier E.S., Keeling P.J.;
RT "The complete sequence of the smallest known nuclear genome from the
RT microsporidian Encephalitozoon intestinalis.";
RL Nat. Commun. 1:77-77(2010).
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|RuleBase:RU003651}.
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DR EMBL; CP001952; ADM12571.1; -; Genomic_DNA.
DR RefSeq; XP_003073931.1; XM_003073885.1.
DR AlphaFoldDB; E0SAE6; -.
DR GeneID; 9699639; -.
DR KEGG; ein:Eint_110710; -.
DR VEuPathDB; MicrosporidiaDB:Eint_110710; -.
DR HOGENOM; CLU_048761_0_0_1; -.
DR OrthoDB; 1343790at2759; -.
DR Proteomes; UP000002313; Chromosome XI.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd19481; RecA-like_protease; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23074; AAA DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23074:SF83; VESICLE-FUSING ATPASE; 1.
DR Pfam; PF00004; AAA; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Proteasome {ECO:0000313|EMBL:ADM12571.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 79..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 172..345
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 453 AA; 52241 MW; 56ACF915A3003CDD CRC64;
MRDLEASKNY KVENKTAEDE EEYEKVKNRT KDNKPEEKKR DINNDILGAL IYRKILKDYG
IKKKPKTEKT KDTSGGTKGV LYLIIIILVF AYVIYRIIVS EGGGSIGKTS KEKDEKMEDQ
DKPSFRDGST FENVPYFGKE DLMIQVISQV TKIVSLLRTV PEKELHKTIE TTQRNFLFHG
PPGTGKTLFM KKLIYLVDLN IKFLKMRSEI GEEEFDRMDH NEKLVRARQM ESLTRITFVT
PSSLNNKYVG ETEKNIRALF QSANDGNYWA SFVFIDEVDV FFSKRSDRSQ DYTLKAQTEF
LNTIGGACDK VNSNVFLFGA TNLYDSLDDA FKRRFSGVYE FQLPNDEERL EILEEYLGDC
KKEITNRFND LIRMTNGMAQ SRIVDVLKKI SFANDGNVDR ISWNDLVRAL EDGDPKKKGT
DGSDVSVAKS LKKFYFLEPK PKRRDAEILI TKE
//
