ID E0WUY5_9ENTR Unreviewed; 313 AA.
AC E0WUY5;
DT 02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2010, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Geranyltranstransferase {ECO:0000313|EMBL:EFL91181.1};
GN Name=ispA {ECO:0000313|EMBL:EFL91181.1};
GN ORFNames=REG_1895 {ECO:0000313|EMBL:EFL91181.1};
OS Candidatus Regiella insecticola LSR1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; aphid secondary symbionts; Regiella.
OX NCBI_TaxID=663321 {ECO:0000313|EMBL:EFL91181.1, ECO:0000313|Proteomes:UP000005726};
RN [1] {ECO:0000313|EMBL:EFL91181.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LSR1 {ECO:0000313|EMBL:EFL91181.1};
RX PubMed=19840097;
RA Degnan P.H., Leonardo T.E., Cass B.N., Hurwitz B., Stern D., Gibbs R.A.,
RA Richards S., Moran N.A.;
RT "Dynamics of genome evolution in facultative symbionts of aphids.";
RL Environ. Microbiol. 0:0-0(2009).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; GL379719; EFL91181.1; -; Genomic_DNA.
DR RefSeq; WP_006705526.1; NZ_GL379719.1.
DR AlphaFoldDB; E0WUY5; -.
DR STRING; 663321.REG_1895; -.
DR eggNOG; COG0142; Bacteria.
DR HOGENOM; CLU_014015_0_1_6; -.
DR Proteomes; UP000005726; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000005726};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:EFL91181.1}.
SQ SEQUENCE 313 AA; 34058 MW; 5AD891537FAA3895 CRC64;
MSDLNLPIDF HQQLTLYQRR VDEKLKNFIQ PLPSHSRQLI EAIRYTVLCG GKRIRPYLVY
ATGKMFGLSP GSLDVAAAAV ECIHAYSLVH DDLPAMDDDN LRRGQPSCHI KFGEAIAILA
GDALQTLAFS LLADQPMPNV TLENRLKIVS ELAKAIGAGG MCAGQALDLA AEHCQISLAS
LEKIHRHKTG ALIRAAVRIG ALAAGERSEK TLSLLDDYAD AIGLAFQVQD DILDITGETD
RMGKQQGADQ QRNKSTYSSL LGLEGAKIKA KKFCQDAQIA LDSLASQSLQ DSGASYDTRS
LRALALFIIQ RDR
//
